Results 71 to 80 of about 20,830,634 (309)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Degradation modeling of degradable copolymers for biomimetic scaffolds
Friction, 2019 Biomimetic scaffolds provide a suitable growth environment for tissue engineering and demonstrate good potential for application in biomedical fields.
Taohong Zhang +4 more
doaj +1 more source
Multi-scale mechanobiological model for skeletal muscle hypertrophy
Frontiers in Physiology, 2022 Skeletal muscle adaptation is correlated to training exercise by triggering different signaling pathways that target many functions; in particular, the IGF1-AKT pathway controls protein synthesis and degradation.
Yesid Villota-Narvaez +7 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Multi-scale Modelling of Segmentation [PDF]
Music Perception, 2016 While listening to music, people often unwittingly break down musical pieces into constituent chunks such as verses and choruses. Music segmentation studies have suggested that some consensus regarding boundary perception exists, despite individual differences. However, neither the effects of experimental task (i.e., real-time vs.
Martín Hartmann +2 more
openaire +1 more source
Journal of GlaciologyIn many technical and geomechanics applications, for example tire and ski design or avalanche prediction, the capability to model the mechanical behaviour of snow is of high importance.
Marie Miot +5 more
doaj +1 more source
On Efficient Numerical Algorithms for Simulation of High Power Electrical Cables
Mathematical Modelling and Analysis, 2015 The new virtual modelling tool is constructed, which is used for optimal design of power transmission lines and cables. The construction of such lines should meet the latest power transmission network technical and economical requirements.
Raimondas Čiegis +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
LandSustainable Development Goal 11.7 (SDG 11.7) aims to promote the improvement of urban public spaces. However, the localization process of SDG 11.7 mainly relies on a bottom-up problem-solving approach, which fails to fully encompass the connotation of ...
Kan Wang, Xing Dang, Jianjun Bai
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source