Results 121 to 130 of about 10,180,203 (304)

Advanced Steel Design by Multi-Scale Modeling

open access: yes, 2018
The present contribution highlights the approach to multi-scale steel design used at the Graduate Institute of Ferrous Technology (GIFT). Multi-scale modeling combining ab-initio methods, molecular dynamics, crystal plasticity modeling etc.
Barlat, F   +2 more
core   +2 more sources

Emergency management and urban resilience under seismic risks. Part I: Theoretical approach for quick post-quake damage evaluation of buildings

open access: yesEmergency Management Science and Technology
This paper addresses topics related to emergency management and urban resilience under seismic risk. It focuses on post-seismic structural damage evaluation and urban resilience: the damage suffered by buildings influence the residual capacity for ...
Ahmed Mebarki   +4 more
doaj   +1 more source

Multi-scale and Multimodal Species Distribution Modeling

open access: yes
Published at the CV4Ecology workshop at ECCV 2024 (https://cv4e.netlify.app/papers/06.pdf)
Nina Van Tiel   +5 more
openaire   +4 more sources

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Pore-scale Modeling and Multi-scale Characterization of Liquid Transport in Shales [PDF]

open access: yes, 2018
Distinct from conventional reservoirs, shale formations have limited pore connectivity and unique pore spatial-distribution. Consequently, theoretical pore-network models developed for conventional formations are not representative of the porous media in
Zheng, Da
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

3D fusion modeling of multi-scale geological structures based on subdivision-NURBS surfaces and stratigraphic sequence formalization

open access: yesOpen Geosciences
Multi-scale 3D geological modeling technology is a vital issue to illustrate the complex geological conditions of infrastructure projects at the regional scale, engineering scale, and outcrop scale.
Lyu Mingming   +3 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Spatial analyses on pre-earthquake ionospheric anomalies and magnetic storms observed by China seismo-electromagnetic satellite in August 2018

open access: yesGeoscience Letters
The China Seismo-Electromagnetic Satellite (CSES), with a sun-synchronous orbit at 507 km altitude, was launched on 2 February 2018 to investigate pre-earthquake ionospheric anomalies (PEIAs) and ionospheric space weather.
Jann-Yenq Tiger Liu   +17 more
doaj   +1 more source

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