Results 91 to 100 of about 9,428,499 (297)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Geo-spatial Information ScienceSpatial datasets covering the same area often exist as separate layers, which differ in scale and source. The spatial relations between matching features located at different layers can be retrieved through a computationally demanding process based on ...
Amin Gholami +2 more
doaj +1 more source
Face Recognition by Cortical Multi-scale Line and Edge Representations [PDF]
, 2006 Empirical studies concerning face recognition suggest that faces may be stored in memory by a few canonical representations. Models of visual perception are based on image representations in cortical area V1 and beyond, which contain many cell layers for feature extraction. Simple, complex and end-stopped cells provide input for line, edge and keypoint
Rodrigues, J. M. F., du Buf, J. M. H.
openaire +3 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Applied SciencesWith the widespread application of high-speed and heavy-load railways, the real-time detection of track surface defects has become increasingly crucial. To address the challenges in rail defect detection, this study proposes the PerMSCA-YOLO model, which
Jialiang Zhang +3 more
doaj +1 more source
Multi-scale Cortical Keypoint Representation for Attention and Object Detection [PDF]
, 2005 Keypoints (junctions) provide important information for focus-of-attention (FoA) and object categorization/recognition. In this paper we analyze the multi-scale keypoint representation, obtained by applying a linear and quasi-continuous scaling to an optimized model of cortical end-stopped cells, in order to study its importance and possibilities for ...
Rodrigues, J. M. F., du Buf, J. M. H.
openaire +3 more sources
Application Integration Control System for Multi-Scale and Multi-PhysicsSimulation [PDF]
, 2010 In the case of long-period and large-scale simulation, unexpected stop which is caused by execution time excess, outage of computers, outage of a network during file transfer and so on, become major issues.
SUZUKI, Yoshio +7 more
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source