Results 81 to 90 of about 8,052,059 (334)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Availability of UAV Fleet Evaluation Based on Multi-State System

open access: yesIEEE Access
Unmanned Aerial Vehicle (UAV) applications are extended extremely. Some applications need to use several UAVs for a general mission which can be considered a UAV fleet.
Elena Zaitseva   +4 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Linear-Extended-State-Observer Based Pinning Control of Nonlinear Multi-Robots System

open access: yesIEEE Access, 2020
In this paper, the pinning control problem of nonlinear multi-robots system (MRS) is investigated. By introducing Linear-Extended-State-Observer (LESO) approach, a LESO based pinning control algorithm is proposed for the multi-robots system with non ...
Zhengguang Ma   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Distinct Hadley circulation attributable to rapid and slow El Niño decay and its regional impacts

open access: yesnpj Climate and Atmospheric Science
El Niño significantly impacts the global Hadley circulation (HC), however, the modulation of different decay rates of El Niño on the HC is overlooked.
Xuanliang Ji   +3 more
doaj   +1 more source

Dynamic Reliability Assessment for Multi-State Degraded Systems

open access: yesChemical Engineering Transactions, 2013
With the aim of tracking the deteriorating process of a specific individual multi-state system consisting of more than one multi-state component, a dynamic reliability assessment method which can utilize system-level observation history to dynamically ...
Y. Liu, M.J. Zuo, H.Z. Huang
doaj   +1 more source

A software toolkit for web-based virtual environments based on a shared database [PDF]

open access: yes, 2004
We propose a software toolkit for developing complex web-based user interfaces, incorporating such things as multi-user facilities, virtual environments (VEs), and interface agents.
Dijk, E.M.A.G. van   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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