Results 61 to 70 of about 8,961,197 (295)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2014 A typical approach to handle the complexity of multi-faceted decision-making problems is to use multi-attribute decision-making (MADM) methods based on pairwise comparisons.
Shams, Farhad +2 more
core +1 more source
, 2020 In plenty of realistic situations, multi-attribute group decision-making (MAGDM) is ubiquitous and significant in daily activities of individuals and organizations. Among diverse tools for coping with MAGDM, granular computing-based approaches constitute
Deyu Li +5 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Transport, 2010 Regional aircraft are playing a significant role in airline operations. This paper considers the problem of selecting an appropriate aircraft from the airline fleet for optimal regional air travel realization. Complexity balance between air travel demand
O. Čokorilo +3 more
doaj +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Multi attribute Decision Making Method in the Information Security Solution
工程科学与技术, 2008 :To decide the selection of information security solution, a Multi attribute decision making method was given. The factors which affected the selection were analyzed, including the expense of purchasing the security devices, the cost of operating and ...
胡勇, 郭东军, 吴少华
doaj
The Interval Cognitive Network Process for Multi-Attribute Decision-Making [PDF]
Symmetry, 2017 Aiming at combining the good characteristics of a differential scale in representing human cognition and the favorable properties of interval judgments in expressing decision-makers’ uncertainty, this paper proposes the interval cognitive network process (I-CNP) to extend the primitive cognition network process (P-CNP) to handle interval judgments. The
Xiuli Qi +3 more
openaire +3 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source