Results 71 to 80 of about 8,961,197 (295)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
, 2023 In this article, the parameter of the decision maker’s familiarity with the attributes of the alternatives is introduced for the first time in dynamic multi-attribute group decision making to avoid the disadvantages arising from the inappropriate ...
Fu Zhang, Weimin Ma, Hongwei Ma
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Exemplar-based inference in multi-attribute decision making [PDF]
Judgment and Decision Making, 2008 Several studies propose that exemplar retrieval contributes to multi-attribute decisions. The authors have proposed a process theory enabling a priori predictions of what cognitive representations people use as input to their judgment process (extit ...
Linnea Karlsson +2 more
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Decision-making Strategies and Performance among Seniors [PDF]
Using paper and pencil experiments administered in senior centers, we examine decision-making performance in multi-attribute decision problems. We find a significant decline in performance with age due to reduced reliance on common heuristics among our ...
Mikhael Shor +3 more
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
, 2020 The process of decision-making is subject to various influence factors and environmental uncertainties, which makes decision become a very complex task. As a new type of decision processing tool, the q-rung orthopair fuzzy sets can effectively deal with ...
Zaoli Yang, Bowen Hou, Ping He
core +1 more source
, 2023 The ongoing research in the field of decision-making can be analyzed from different perspectives. Research trends indicate that multi-attribute decision-making (MADM) methods have a significant impact on engineering and management scientific areas. Since
Danijela Tadić, Aleksandar Aleksić
core +1 more source