Results 11 to 20 of about 5,798,326 (260)

Treatment of Multi-Drug Resistant Gram-Negative Bacterial Pathogenic Infections

Journal of Pure and Applied Microbiology, 2020
The multidrug-resistant Gram-negative bacteria (MDR-GNB) infections in severely infected patients present numerous difficulties in terms of treatment failure where antibiotics cannot arrest such drug resistant bacteria.
Wardah Mohammad Akram, Godfred Antony Menezes, Nida Abbas, Wasim Ahmad, Ahmed Mohamed Ahmed   +4 more
doaj   +2 more sources

Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa [PDF]

, 2013
South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included
Pillay, Manormoney, van Helden, Paul D., Nicolaas C. Gey van Pittius (173264), Paul D. van Helden (33594), Marlein E Bosman, Gagneux, Sebastien, Thomas C Victor, Manormoney Pillay (257769), Nicolaas C Gey van Pittius, Borna Müller (173253), Hayes, Cindy, Streicher, Elizabeth M., Andre Trollip (449922), Robin M Warren, Elizabeth M Streicher, Trollip, Andre, Violet N. Chihota (143307), Warren, Robin M., Bosman, Marlein E., Müller, Borna, Violet N Chihota, Cindy Hayes, Marisa Klopper (398815), Cindy Hayes (449923), Elizabeth M. Streicher (439727), Borna Müller, Paul D van Helden, Marlein E. Bosman (449924), Klopper, Marisa, Gerrit Coetzee, Sebastien Gagneux (149824), Chihota, Violet N., Andre Trollip, Marisa Klopper, Sebastien Gagneux, Gerrit Coetzee (296078), Victor, Thomas C., Manormoney Pillay, Coetzee, Gerrit, Gey van Pittius, Nicolaas C., Robin M. Warren (33593), Thomas C. Victor (185348)   +41 more
core   +2 more sources

Explaining risk factors for drug-resistant tuberculosis in England and Wales: contribution of primary and secondary drug resistance [PDF]

, 2004
Drug-resistant tuberculosis can be transmitted (primary) or develop during the course of treatment (secondary). We investigated risk factors for each type of resistance.
Glynn, JR, Story, A, Hayward, AC, Watson, JM, Conaty, SJ, Drobniewski, FA   +5 more
core   +1 more source

Trends in drug-resistant tuberculosis in a gold-mining workforce in South Africa, 2002-2008. [PDF]

, 2012
SETTING AND OBJECTIVE: To describe trends in drug-resistant tuberculosis (TB) in two gold-mining workforces, South Africa, 2002-2008. DESIGN: TB programme data analysis.
Fielding, K. L., van Halsema, CL, Churchyard, GJ, Churchyard, G. J., Chihota, VN, Grant, AD, Chihota, V. N., Grant, A. D., Fielding, KL, van Halsema, C. L., Lewis, J. J., Lewis, JJ   +11 more
core   +1 more source

Multidrug-resistant tuberculosis. [PDF]

, 2008
BACKGROUND: With almost 9 million new cases each year, tuberculosis remains one of the most feared diseases on the planet. Led by the STOP-TB Partnership and WHO, recent efforts to combat the disease have made considerable progress in a number of ...
Zager, Ellen M, McNerney, Ruth, McNerney Ruth, Zager Ellen M   +3 more
core   +1 more source

Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM) : study protocol for a randomized controlled trial [PDF]

, 2014
Background In contrast to drug-sensitive tuberculosis, the guidelines for the treatment of multi-drug-resistant tuberculosis (MDR-TB) have a very poor evidence base; current recommendations, based on expert opinion, are that patients should be treated ...
Squire, Stephen Bertel, Squire, S Bertel, Patrick PJ Phillips, Madan, Jason, Rusen, I. D., Chiang, Chen-Yuan, Armand Van Deun, Chiang, Chen Yuan, Gabriela Torrea, Phillips, P. (Patrick), Van Deun, Armand, Rusen, ID, Meredith, Sarah K, Jason Madan, Meredith, Sarah K., Nunn, Andrew J, ID Rusen, Nunn, Andrew J., Squire, Bertie, Torrea, Gabriela, Chen-Yuan Chiang, Sarah K Meredith, Phillips, Patrick PJ, Andrew J Nunn, Phillips, Patrick P.J., S Bertel Squire   +25 more
core   +2 more sources

Novel antimicrobial strategies to treat multi‐drug resistant Staphylococcus aureus infections

Microbial Biotechnology, 2023
Antimicrobial resistance is a major obstacle for the treatment of infectious diseases and currently represents one of the most significant threats to global health.
Edward J. A. Douglas, Sri W. Wulandari, Scott D. Lovell, Maisem Laabei   +3 more
doaj   +1 more source

Multi Drug Resistant Klebsiella Isolates in Burn Patients: A Comparative Study [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Infections are the most common complications in the burn patients admitted to the hospitals leading to high morbidity and mortality. Klebsiella is one of the most frequently isolated bacteria from burn wounds.
Naz Perween, S. Kirshna Prakash, Oves Siddiqui   +2 more
doaj   +1 more source

Bacteriophages in Infectious Diseases and Beyond—A Narrative Review

Antibiotics, 2023
The discovery of antibiotics has revolutionized medicine and has changed medical practice, enabling successful fighting of infection. However, quickly after the start of the antibiotic era, therapeutics for infectious diseases started having limitations ...
Petros Ioannou, Stella Baliou, George Samonis   +2 more
doaj   +1 more source

Characterizing the emergence and persistence of drug resistant mutations in HIV-1 subtype C infections using 454 ultra deep pyrosequencing. [PDF]

, 2013
BACKGROUND: The role of HIV-1 RNA in the emergence of resistance to antiretroviral therapies (ARTs) is well documented while less is known about the role of historical viruses stored in the proviral DNA. The primary focus of this work was to characterize
Grace P McCormack, Crampin, Amelia C., Bansode, Vijay, McCormack, Grace P., Glynn, Judith R., Neil French, Ram K Shrestha, Travers, Simon A, Simon A Travers, French, Neil, Glynn, Judith R, Crampin, Amelia C, Vijay Bansode, Judith R Glynn, Vijay Bansode, Amelia C Crampin, McCormack, Grace P, Travers, Simon A., Shrestha, Ram K., Ngwira, Bagrey, Shrestha, Ram K, Bagrey Ngwira, Bansode Vijay, French Neil, Ngwira Bagrey, Crampin Amelia C, McCormack Grace P, Travers Simon A, Glynn Judith R, Shrestha Ram K   +29 more
core   +2 more sources