Results 141 to 150 of about 4,644,920 (368)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Active Methylene-based Multicomponent Reactions under Microwave Heating

CHIMIA, 2011
The use of emerging multicomponent reactions (MCRs) in conjunction with microwave (MW)-assisted chemistry techniques is dramatically reducing chemical waste and reaction times in several organic syntheses and chemical transformations.
Bo Jiang, Shu-Jiang Tu
doaj   +1 more source

Synthesis of tetrahydropyridines by one-pot multicomponent reaction using nano-sphere silica sulfuric acid

Journal of the Iranian Chemical Society, 2015
A highly efficient protocol for the synthesis of 1,2,3,4-tetrahydropyridines in the presence of nano-sphere silica sulfuric acid (NS-SSA) was used for good yields by one-pot multicomponent reaction (MCRs). The reagent nano-sphere silica sulfuric acid (NS-
Masoume Daraei, M. Zolfigol, Fatemeh Derakhshan-Panah, Morteza Shiri, H. Kruger, M. Mokhlesi   +5 more
semanticscholar   +1 more source

Compressible streaming instabilities in rotating thermal viscous objects

, 2009
We study electromagnetic streaming instabilities in thermal viscous regions of rotating astrophysical objects, such as, protostellar and protoplanetary magnetized accretion disks, molecular clouds, their cores, and elephant trunks.
A. K. Nekrasov, Balbus, Braginskii, Caselli, Caselli, Crutcher, Hayashi, Masada, Nekrasov, Pessah, Ruffle, Stanimirović   +11 more
core   +1 more source

Identification of Mannose‐Capped‐Arabinomannan 101‐mer as a Potential Influenza Virus Vaccine Adjuvant

Advanced Science, EarlyView.
Well‐defined and synthetic mannose‐capped arabinomannan 101‐mer from Mycobacterium tuberculosis cell wall was identified as a potent influenza vaccine adjuvant, boosting the antibody response, realizing full protection and showing excellent safety. ABSTRACT Many natural bacterial components as adjuvants can activate the host immune system, but the ...
Yu‐Fang Zhang, Ruihong Xu, Jia Luo, Yuxin Ma, Guozhi Xiao, Ye Liu   +5 more
wiley   +1 more source

An efficient and catalyst-free synthesis of N-arylidene-2-arylimidazo[1,2-a]pyridine-3-ylamine derivatives via Strecker reaction under controlled microwave heating

Green Processing and Synthesis, 2017
An efficient one-pot multicomponent reaction of 2-aminopyridine with aromatic aldehydes and either benzoyl cyanide or cyanamide in pyridine under controlled microwave heating afforded N-aryldene-2-arylimidazo[1,2-a]-pyridine-3-ylamine derivatives.
Abdel Hameed Afaf Mohamed, Moustafa Moustafa Sherief, Al-Mousawi Saleh Mohammed, Awed Reham R., Sadek Kamal Usef   +4 more
doaj   +1 more source

Beyond Sabatier: Multiplicate Spillover Phenomena for Manipulating Catalytic Dynamics in Various Electrocatalysis

Advanced Science, EarlyView.
Various spillover‐mediated electrocatalytic reactions, such as hydrogen and oxygen evolution, carbon dioxide and nitrogen reduction, and methanol oxidization reactions, are systematically summarized. Abstract Spillover phenomenon, which is characterized by the dynamic migration of active species across catalyst surfaces, provides a promising avenue to ...
Di Wang, Ziyou Dong, Qianqian Yao, Shixue Dou, Jun Mei, Ziqi Sun   +5 more
wiley   +1 more source

Modular assembly of indole alkaloids enabled by multicomponent reaction. [PDF]

Nat Commun, 2023
Li J, Lai Z, Zhang W, Zeng L, Cui S.
europepmc   +1 more source

New multicomponent reactions in water: a facile synthesis of 1,3-dioxo-2-indanilidene-heterocyclic scaffolds and indenoquinoxalines through reaction of ninhydrin-malononitrile adduct with diverse N-binucleophiles

, 2022
Zahra Rahimi, Mohammad Bayat, Hajar Hosseini   +2 more
openalex   +2 more sources

Polyoxometalate as Hydrogen–Electron Hub in Metal–Organic Complex for Electrocatalytic Nitrate Reduction to Ammonia

Advanced Science, EarlyView.
To tackle low electrocatalytic nitrate reduction to ammonia efficiency in neutral media, this work designs chain‐like dinuclear/trinuclear polyoxometalate‐based metal‐organic complexes. Metal clusters provide nitrate adsorption/activation sites, while polyoxometalates (POMs) drive water dissociation to generate active hydrogen (*H) that migrates to ...
Qiushuang Jiang, Xinming Wang, Shengji Tian, Haijun Pang, Yongbin Song, Huiyuan Ma   +5 more
wiley   +1 more source