Results 121 to 130 of about 26,762 (251)

STING antagonists, synthesized via Povarov-Doebner type multicomponent reaction. [PDF]

open access: yesRSC Med Chem, 2023
Ong WWS   +4 more
europepmc   +1 more source

A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers

open access: yesAdvanced Science, EarlyView.
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels   +2 more
wiley   +1 more source

Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs. [PDF]

open access: yesInt J Mol Sci, 2023
Graziano G   +8 more
europepmc   +1 more source

Hydrogen‐Bonding‐Directed Assembly of COF/Nanocluster Hybrids With Synergistic Roles for Efficient Solar Hydrogen Production

open access: yesAdvanced Science, EarlyView.
Hydrogen‐bonding‐directed assembly enables molecular‐level integration of a covalent organic framework and NiZnCo nanoclusters. The engineered interface couples directional charge transfer, multimetal synergy, and photothermal‐assisted catalysis, providing a versatile strategy for efficient noble‐metal‐free solar hydrogen production.
Ailing Pan   +5 more
wiley   +1 more source

Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction

open access: yesAdvanced Science, EarlyView.
Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen   +5 more
wiley   +1 more source

Exploring the Synthetic Potential of γ-Lactam Derivatives Obtained from a Multicomponent Reaction-Applications as Antiproliferative Agents. [PDF]

open access: yesMolecules, 2022
López-Francés A   +5 more
europepmc   +1 more source

Data‐Driven Design of Self‐Adhesive Epidermal Electrodes and Sensors

open access: yesAdvanced Science, EarlyView.
This work presents self‐adhesive, stretchable epidermal electrodes and sensors developed through a data‐driven design framework that integrates artificial neural networks with genetic algorithms. By tailoring optimization objectives, either maximizing electrical conductivity and adhesion or enhancing piezoresistive sensitivity, the study enables the ...
Xuan Li   +10 more
wiley   +1 more source

Click Chemistry and Multicomponent Reaction for Linker Diversification of Zinc Dipicolylamine-Based Drug Conjugates. [PDF]

open access: yesFront Chem, 2021
Tsai CH   +7 more
europepmc   +1 more source

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