STING antagonists, synthesized via Povarov-Doebner type multicomponent reaction. [PDF]
Ong WWS +4 more
europepmc +1 more source
A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs. [PDF]
Graziano G +8 more
europepmc +1 more source
Hydrogen‐bonding‐directed assembly enables molecular‐level integration of a covalent organic framework and NiZnCo nanoclusters. The engineered interface couples directional charge transfer, multimetal synergy, and photothermal‐assisted catalysis, providing a versatile strategy for efficient noble‐metal‐free solar hydrogen production.
Ailing Pan +5 more
wiley +1 more source
Imidazo[1,2-a]pyridine derivatives synthesis from lignin β-O-4 segments via a one-pot multicomponent reaction. [PDF]
Guo L +7 more
europepmc +1 more source
Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction
Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen +5 more
wiley +1 more source
Exploring the Synthetic Potential of γ-Lactam Derivatives Obtained from a Multicomponent Reaction-Applications as Antiproliferative Agents. [PDF]
López-Francés A +5 more
europepmc +1 more source
Data‐Driven Design of Self‐Adhesive Epidermal Electrodes and Sensors
This work presents self‐adhesive, stretchable epidermal electrodes and sensors developed through a data‐driven design framework that integrates artificial neural networks with genetic algorithms. By tailoring optimization objectives, either maximizing electrical conductivity and adhesion or enhancing piezoresistive sensitivity, the study enables the ...
Xuan Li +10 more
wiley +1 more source
An electrochemical multicomponent reaction toward C-H tetrazolation of alkyl arenes and vicinal azidotetrazolation of alkenes. [PDF]
Yu Y, Zhu XB, Yuan Y, Ye KY.
europepmc +1 more source
Click Chemistry and Multicomponent Reaction for Linker Diversification of Zinc Dipicolylamine-Based Drug Conjugates. [PDF]
Tsai CH +7 more
europepmc +1 more source

