Results 1 to 10 of about 126 (118)

Enediyne-Comprising Amino Aldehydes in the Passerini Reaction

ACS Combinatorial Science, 2018
Multicomponent reactions represent a highly efficient approach to a broad spectrum of structurally diverse compounds starting from simple and affordable compounds. A focused library of tweezers-like compounds is prepared by employing the multicomponent Passerini reaction comprising enediyne-derived amino aldehydes.
Ivanka Jeric, Matija Gredičak
exaly   +3 more sources

Green and three-component synthesis of 2-cyclohexylamino-2-oxo-1-arylethyl/alkyl thiophene-3-carboxylates in aqueous medium [PDF]

شیمی کاربردی روز, 2021
From the Passerini three-component reaction between cyclohexyl isocyanide, thiophene-2-carboxylic acid and aryl/alkyl aldehydes, some new compounds of 2-cyclohexylamino-2-oxo-1-arylethyl/alkyl thiophene-3-carboxylates have been synthesized in 30-45 min ...
sima mosavi niaraki, abbas azimi roshan, Aazam Monfared, hamze kiani   +3 more
doaj   +1 more source

Synthesis of Depsipeptides via Isocyanide-Based Consecutive Bargellini–Passerini Multicomponent Reactions

SynOpen, 2021
An efficient and straightforward approach has been established for the preparation of a new class of depsipeptide structures via isocyanide-based consecutive Bargellini–Passerini multicomponent reactions.
Hassan Farhid, Mohammad Mahdi Rostami, Ahmad Shaabani, Behrouz Notash   +3 more
doaj   +1 more source

Keto-Enol Tautomerism in Passerini and Ugi Adducts

Molecules, 2021
The use of arylglyoxal as starting material in Passerini and Ugi reactions affords β-ketoamides. This has allowed to study keto-enol tautomerism in these systems and assess the way in which the presence of acyloxy or aminoacyl groups bound to the C2 ...
Pablo Pertejo, Andrea Sancho-Medina, Tomás Hermosilla, Beatriz González-Saiz, Javier Gómez-Ayuso, Roberto Quesada, Daniel Moreno, Israel Carreira-Barral, María García-Valverde   +8 more
doaj   +1 more source

New efficient synthesis of polysubstituted 3,4-dihydroquinazolines and 4H-3,1-benzothiazines through a Passerini/Staudinger/aza-Wittig/addition/nucleophilic substitution sequence

Beilstein Journal of Organic Chemistry, 2022
A new efficient synthesis of polysubstituted 3,4-dihydroquinazolines and 4H-3,1-benzothiazines via sequential Passerini/Staudinger/aza-Wittig/addition/nucleophilic substitution reaction has been developed.
Long Zhao, Mao-Lin Yang, Min Liu, Ming-Wu Ding   +3 more
doaj   +1 more source

Synthesis of Triterpenoid-Derived α-Acyloxycarboxamides via Passerini Reaction

Chemistry Proceedings, 2021
Herein we describe the synthesis of a small series of α-acyloxycarboxamides via a facile and efficient one-pot procedure, employing a plant-derived triterpenoid as carboxylic acid component.
Fidel Rodríguez-López, Hugo A. García-Gutiérrez, Rocío Gámez-Montaño   +2 more
doaj   +1 more source

The 100 facets of the Passerini reaction

Chemical Science, 2021
This perspective aims at celebrating the 100th anniversary of the discovery of the Passerini three component reaction.
Banfi L., Basso A., Lambruschini C., Moni L., Riva R.   +4 more
openaire   +3 more sources

Stereochemical Control of the Passerini Reaction. [PDF]

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Peter R, Andreana, Chang C, Liu, Stuart L, Schreiber   +2 more
openaire   +3 more sources

Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators

Scientific Reports, 2022
Selective elimination of tumors has always been the mainstay of oncology research. The on-going research underlying the cellular apoptotic mechanisms reveal caspases activation, especially the key effector caspase-3, as a personalized tumor-selective ...
Mohammed Salah Ayoup, Yasmin Wahby, Hamida Abdel-Hamid, Marwa M. Abu-Serie, Mohamed Teleb   +4 more
doaj   +1 more source

Strain and Complexity, Passerini and Ugi Reactions of Four‐Membered Heterocycles and Further Elaboration of TOSMIC Product

ChemistryOpen, 2023
Straightforward and general Passerini and Ugi procedures have been developed to incorporate four‐membered heterocycles into highly functionalized scaffolds.
Gábor Sztanó, Dr. Zoltán Dobi, Dr. Tibor Soós   +2 more
doaj   +1 more source