Results 21 to 30 of about 7,368,504 (211)
Accessing Promising Passerini Adducts in Anticancer Drug Design [PDF]
MoleculesThe 3-component Passerini reaction (3CPR), discovered little more than 100 years ago, has been demonstrated in the last few decades to be a valuable tool for accessing structural diversity and complexity, essential topics to consider in drug discovery ...
Ana Margarida Janeiro +3 more
doaj +2 more sources
Innovative synthesis of drug-like molecules using tetrazole as core building blocks [PDF]
Beilstein Journal of Organic ChemistryTetrazole is widely utilized as a bioisostere for carboxylic acid in the field of medicinal chemistry and drug development, enhancing the drug-like characteristics of various molecules.
Jingyao Li +3 more
doaj +2 more sources
ChemistryThe facile generation of the α-acyloxy carboxamide radical is hereby reported for the first time, utilizing a photoredox catalyzed reaction of Passerini adducts synthesized using a 4-formyl-1,4-dihydropyridine as the carbonyl component.
Francesca Brunelli +5 more
semanticscholar +2 more sources
Green and three-component synthesis of 2-cyclohexylamino-2-oxo-1-arylethyl/alkyl thiophene-3-carboxylates in aqueous medium [PDF]
شیمی کاربردی روز, 2021 From the Passerini three-component reaction between cyclohexyl isocyanide, thiophene-2-carboxylic acid and aryl/alkyl aldehydes, some new compounds of 2-cyclohexylamino-2-oxo-1-arylethyl/alkyl thiophene-3-carboxylates have been synthesized in 30-45 min ...
sima mosavi niaraki +3 more
doaj +1 more source
Stereochemical control of the Passerini reaction. [PDF]
Org Lett, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Andreana PR, Liu CC, Schreiber SL.
europepmc +5 more sources
Kinetics and Mechanism of the Enantioselective Passerini Multicomponent Reaction Catalyzed by Chiral Ionic Liquids [PDF]
ACS OmegaJuliana Santos +8 more
doaj +2 more sources
SynOpen, 2021 An efficient and straightforward approach has been established for the preparation of a new class of depsipeptide structures via isocyanide-based consecutive Bargellini–Passerini multicomponent reactions.
Hassan Farhid +3 more
doaj +1 more source
Keto-Enol Tautomerism in Passerini and Ugi Adducts
Molecules, 2021 The use of arylglyoxal as starting material in Passerini and Ugi reactions affords β-ketoamides. This has allowed to study keto-enol tautomerism in these systems and assess the way in which the presence of acyloxy or aminoacyl groups bound to the C2 ...
Pablo Pertejo +8 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2022 A new efficient synthesis of polysubstituted 3,4-dihydroquinazolines and 4H-3,1-benzothiazines via sequential Passerini/Staudinger/aza-Wittig/addition/nucleophilic substitution reaction has been developed.
Long Zhao +3 more
doaj +1 more source
, 2022 A simple Passerini reaction using acetic acid, benzaldehyde and methyl isocyanoacetate, that is is complete in 40 minutes. The product can be purified via recrystallization.
Loy, Rebecca
core +1 more source