Synthesis of Glycomimetics by Diastereoselective Passerini Reaction.
The Journal of Organic Chemistry, 2018 We describe the utilization of bis-isopropylidene-protected d-fructose-derived aldehyde in the Passerini reaction with various acids and isocyanides. A library of densely functionalized glycomimetics bearing up to 3 carbohydrate units was obtained in ...
K. VLAHOVIČEK-KAHLINA +4 more
semanticscholar +5 more sources
An efficient Passerini tetrazole reaction (PT-3CR) [PDF]
Green Chemistry, 2016 A sonication accelerated, catalyst free, simple, high yielding and efficient method for the Passerini-type three-component reaction (PT-3CR) has been developed.
Chandgude, Ajay L.; Domling, Alexander
openaire +6 more sources
Unconventional Passerini Reaction toward α-Aminoxy-amides. [PDF]
Organic Letters, 2016 The Passerini multicomponent reaction (P-3CR) toward the one-step synthesis of α-aminoxy-amide, by employing for the first time a N-hydroxamic acid component, has been reported. The sonication-accelerated, catalyst-free, simple, fast, and highly efficient Passerini reaction is used for the synthesis of diverse α-aminoxy-amides.
Ajay L. Chandgude, A. Dömling
semanticscholar +6 more sources
Artificial Macrocycles by Ugi Reaction and Passerini Ring Closure [PDF]
The Journal of Organic Chemistry, 2016 Artificial macrocycles can be convergently synthesized by a sequence of an Ugi multicomponent reaction (MCR) followed by an intramolecular Passerini MCR used to close the macrocycle. Significantly, in this work, the first intramolecular macrocyclization through a Passerini reaction is described. We describe 21 macrocycles of a size of 15-20.
Abdelraheem +4 more
core +7 more sources
Creating unimolecular multivalent diversity in protein conjugates via the Passerini multicomponent bioconjugation with isocyanoproteins [PDF]
Communications ChemistryThe ability to conjugate multiple molecules to a protein is of great interest for pharmaceutical and vaccine development, especially if this can be achieved in a one-pot procedure.
Ana R. Humpierre +11 more
doaj +2 more sources
Light-Controlled Modulation of 15-Lipoxygenase-1 Regulates Intestinal Inflammatory Signaling. [PDF]
Angew Chem Int Ed EnglThe developed target‐guided strategy enables the rational design of diazo‐based photoswitchable inhibitors of 15‐lipoxygenase‐1. Distinct molecular architectures program opposite light‐dependent activity, allowing on‐demand control of enzyme inhibition.
Louka A +10 more
europepmc +3 more sources
Catalytic Enantioselective Passerini Three‐Component Reaction
Angewandte Chemie International Edition, 2007 A [(salen)-AlIIICl] complex catalyzes the Passerini three-component reaction of an aldehyde, a carboxylic acid, and an isocyanide to afford alpha -acyloxyamides, e.g., I, with good to excellent enantioselectivity. A variety of nonchelating substrates can be used to generate the versatile chiral products. [on SciFinder (R)]
Wang, Shi-Xin +3 more
openaire +4 more sources
Orbital-Hybridizable Nanoseed Interphase Enables One-Minute Rechargeable, Energy-Dense Anode-Free Aqueous Zinc Batteries. [PDF]
Adv MaterAn orbital‐hybridizable nanoseed (OHNS) interphase induces strong orbital hybridization between Zn and carbon edges, accelerating Zn nucleation while suppressing 2D surface diffusion. This interfacial electronic regulation drives uniform, dense, and (002)‐oriented Zn growth, enabling stable and fast charging behavior in anode‐free aqueous Zn batteries.
Kim WY +16 more
europepmc +2 more sources
Passerini reaction: Synthesis and applications in polymer chemistry
European Polymer Journal, 2023 Prashant Kumar +2 more
exaly +2 more sources
Introducing Multicomponent Reactions to Polymer Science: Passerini Reactions of Renewable Monomers
Journal of the American Chemical Society, 2011 Combination of the Passerini three component-reaction (3CR) and olefin metathesis led to the formation of poly[1-(alkyl carbamoyl)alkyl alkanoates], a new class of polyesters with amide moieties in their side chain, from renewable resources. Two different approaches were studied and compared to each other.
Kreye, O., Tóth, T., Meier, M. A. R.
core +6 more sources