Results 11 to 20 of about 126 (118)

Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis

open access: yesNature Communications, 2021
Multicomponent reactions enable the rapid construction of diverse molecular scaffolds with modularity and step economy. In this work, the authors report the use of boronic acids as carbon nucleophiles in a Passerini-type three-component coupling reaction
Kai Yang   +5 more
doaj   +1 more source

O‐Arylative Passerini Reactions. [PDF]

open access: yesChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
El Kaim, Laurent   +2 more
openaire   +2 more sources

Mechanochemically‐Assisted Passerini Reactions: A Practical and Convenient Method for the Synthesis of Novel α‐Acyloxycarboxamide Derivatives

open access: yesChemistryOpen, 2023
A carboxylic acid, an aldehyde, and an isonitrile were combined in a single step (Passerini reaction) under mechanochemical activation to produce several α‐acyloxycarboxamide derivatives in high to excellent yields within 15 min of milling ...
Dr. Sodeeq Aderotimi Salami   +3 more
doaj   +1 more source

Plant-Derived Triterpenoid Functionalization: Synthesis of α-Acyloxycarboxamides

open access: yesChemistry Proceedings, 2023
The application of isocyanide-based multicomponent reactions (IMCRs) for triterpenoid functionalization has been little reported. Triterpenoids and their derivatives are an important class of natural products of interest in medicinal chemistry due to ...
Fidel Rodriguez-Lopez   +3 more
doaj   +1 more source

Synthesis of structurally diverse 3,4-dihydropyrimidin-2(1H)-ones via sequential Biginelli and Passerini reactions

open access: yesBeilstein Journal of Organic Chemistry, 2017
The Biginelli reaction was combined with the Passerini reaction for the first time in a sequential multicomponent tandem reaction approach. After evaluation of all possible linker components and a suitable solvent system, highly functionalized ...
Andreas C. Boukis   +2 more
doaj   +1 more source

Phosphonanaloga von Aminosäuren und Peptiden: Synthese der Phosphonanaloga von Depsipeptiden mittels der Passerini-Reaktion.

open access: yesCHIMIA, 1983
Synthesis of phosphorous analogues of tri- and tetra-depsipeptides 4 involving the Passerini reaction of diethylisocyanmethylphosphonate 3 with carbonyl compounds 2 and N-protected glycine 1 is reported.
Janusz Rachoń
doaj   +1 more source

Green synthesis, crystal structure, and antifungal activities of (E)-4-arylidene-5-oxotetrahydrofuran

open access: yesFrontiers in Chemistry, 2022
A series of γ-lactone derivatives (E)-4-arylidene-5-oxotetrahydrofuran derivatives were synthesized via a tandem Passerini 3CC/SN cyclization microwave-assisted one-pot method efficiently starting from Baylis Hillman acids, aryl glyoxals and isocyanides,
Yun Dong   +11 more
doaj   +1 more source

Efficient Synthesis of Boron-Containing α-Acyloxyamide Analogs via Microwave Irradiation

open access: yesMolecules, 2013
In this report, a Passerini three-component reaction utilizing boron-containing carboxylic acids or aldehydes is discussed. The reaction was carried out in water and facilitated by the use of microwave irradiation.
Po-Shen Pan   +6 more
doaj   +1 more source

Protection-Free Strategy for the Synthesis of Boro-Depsipeptides in Aqueous Media under Microwave-Assisted Conditions

open access: yesMolecules, 2022
In this report, 19 boron-containing depsipeptides were synthesized via microwave-assisted Passerini three-component reaction (P-3CR) in an aqueous environment.
Shuo-Bei Qiu   +11 more
doaj   +1 more source

Passerini Reactions on Biocatalytically Derived Chiral Azetidines [PDF]

open access: yesMolecules, 2016
The purpose of this study was to explore a series of Passerini reactions on a biocatalytically derived enantiopure azetidine-2-carboxyaldehyde in order to obtain, in a diastereoselective manner, polyfunctionalised derivatives having the potential to be cyclized to chiral bridged bicyclic nitrogen heterocycles.
MONI, LISA   +6 more
openaire   +3 more sources

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