Results 31 to 40 of about 7,368,504 (211)

Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators

Scientific Reports, 2022
Selective elimination of tumors has always been the mainstay of oncology research. The on-going research underlying the cellular apoptotic mechanisms reveal caspases activation, especially the key effector caspase-3, as a personalized tumor-selective ...
Mohammed Salah Ayoup, Yasmin Wahby, Hamida Abdel-Hamid, Marwa M. Abu-Serie, Mohamed Teleb   +4 more
doaj   +1 more source

Strain and Complexity, Passerini and Ugi Reactions of Four‐Membered Heterocycles and Further Elaboration of TOSMIC Product

ChemistryOpen, 2023
Straightforward and general Passerini and Ugi procedures have been developed to incorporate four‐membered heterocycles into highly functionalized scaffolds.
Gábor Sztanó, Dr. Zoltán Dobi, Dr. Tibor Soós   +2 more
doaj   +1 more source

O‐Arylative Passerini Reactions. [PDF]

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
El Kaim, Laurent, Gizolme, Marie, Grimaud, Laurence   +2 more
openaire   +2 more sources

Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis

Nature Communications, 2021
Multicomponent reactions enable the rapid construction of diverse molecular scaffolds with modularity and step economy. In this work, the authors report the use of boronic acids as carbon nucleophiles in a Passerini-type three-component coupling reaction
Kai Yang, Feng Zhang, Tongchang Fang, Chaokun Li, Wangyang Li, Qiuling Song   +5 more
doaj   +1 more source

Merging the Passerini reaction with chemo-enzymatic synthesis for C-terminal peptide modification

Cell Reports Physical Science
Peptide and protein synthesis, as well as bioconjugation, are increasingly important for developing site-selective modifications in biomedical applications.
J. Hanssens, Sam van Dun, Tessa H.G. Lokate, V. R. Reinartz, L. J. van den Bos, Romano V. A. Orru, Jordy M. Saya   +6 more
semanticscholar   +2 more sources

Hydrophobization of carboxymethyl cellulose by Passerini reaction: towards films with improved water vapor barrier properties

Journal of Membrane Science
International audienceTo address the need for developing sustainable materials with effective barriers to water vapor, this work explores the potential of self-supported films made of carboxymethyl cellulose (CMC) functionalized by the Passerini three ...
C. Vuillet, Valérie Guillard, H. Angellier-Coussy, G. Sudre, F. Gouanvé, E. Fleury, A. Charlot   +6 more
semanticscholar   +2 more sources

Mechanochemically‐Assisted Passerini Reactions: A Practical and Convenient Method for the Synthesis of Novel α‐Acyloxycarboxamide Derivatives

ChemistryOpen, 2023
A carboxylic acid, an aldehyde, and an isonitrile were combined in a single step (Passerini reaction) under mechanochemical activation to produce several α‐acyloxycarboxamide derivatives in high to excellent yields within 15 min of milling ...
Dr. Sodeeq Aderotimi Salami, Justin Bazibuhe Safari, Dr. Vincent J. Smith, Prof. Dr. Rui W. M. Krause   +3 more
doaj   +1 more source

Plant-Derived Triterpenoid Functionalization: Synthesis of α-Acyloxycarboxamides

Chemistry Proceedings, 2023
The application of isocyanide-based multicomponent reactions (IMCRs) for triterpenoid functionalization has been little reported. Triterpenoids and their derivatives are an important class of natural products of interest in medicinal chemistry due to ...
Fidel Rodriguez-Lopez, Edgar G. Rodríguez-García, Hugo A. García-Gutiérrez, Rocío Gámez-Montaño   +3 more
doaj   +1 more source

Four-Component One-Pot Process Involving Passerini Reaction Followed by Aldol Addition and Transesterification

Annalen der Pharmacie, 2020
A four-component one-pot transformation involving the Passerini reaction, an aldol addition, and a transesterification has been elaborated, providing an access to a library of densely functionalized tartaric acid derivatives.
M. Hasan, Manzoor Zaman, Anatoly A Peshkov, Niyaz Amire, Adil Les, Anton A. Nechaev, Yuqing Wang, S. Kashtanov, E. V. Van der Eycken, Olga P. Pereshivko, Vsevolod A. Peshkov   +10 more
semanticscholar   +2 more sources

Synthesis of structurally diverse 3,4-dihydropyrimidin-2(1H)-ones via sequential Biginelli and Passerini reactions

Beilstein Journal of Organic Chemistry, 2017
The Biginelli reaction was combined with the Passerini reaction for the first time in a sequential multicomponent tandem reaction approach. After evaluation of all possible linker components and a suitable solvent system, highly functionalized ...
Andreas C. Boukis, Baptiste Monney, Michael A. R. Meier   +2 more
doaj   +1 more source