Results 31 to 40 of about 1,960 (188)

Synthesis of structurally diverse 3,4-dihydropyrimidin-2(1H)-ones via sequential Biginelli and Passerini reactions

Beilstein Journal of Organic Chemistry, 2017
The Biginelli reaction was combined with the Passerini reaction for the first time in a sequential multicomponent tandem reaction approach. After evaluation of all possible linker components and a suitable solvent system, highly functionalized ...
Andreas C. Boukis, Baptiste Monney, Michael A. R. Meier   +2 more
doaj   +1 more source

Phosphonanaloga von Aminosäuren und Peptiden: Synthese der Phosphonanaloga von Depsipeptiden mittels der Passerini-Reaktion.

CHIMIA, 1983
Synthesis of phosphorous analogues of tri- and tetra-depsipeptides 4 involving the Passerini reaction of diethylisocyanmethylphosphonate 3 with carbonyl compounds 2 and N-protected glycine 1 is reported.
Janusz Rachoń
doaj   +1 more source

Green synthesis, crystal structure, and antifungal activities of (E)-4-arylidene-5-oxotetrahydrofuran

Frontiers in Chemistry, 2022
A series of γ-lactone derivatives (E)-4-arylidene-5-oxotetrahydrofuran derivatives were synthesized via a tandem Passerini 3CC/SN cyclization microwave-assisted one-pot method efficiently starting from Baylis Hillman acids, aryl glyoxals and isocyanides,
Yun Dong, Yun Dong, Ling-Qi Kong, Ling-Qi Kong, Qin-Hua Chen, Bin Li, Xiao-Hua Zeng, Xiao-Hua Zeng, Li-Na Ke, Li-Na Ke, Hong-Mei Wang, Hong-Mei Wang   +11 more
doaj   +1 more source

Efficient Synthesis of Boron-Containing α-Acyloxyamide Analogs via Microwave Irradiation

Molecules, 2013
In this report, a Passerini three-component reaction utilizing boron-containing carboxylic acids or aldehydes is discussed. The reaction was carried out in water and facilitated by the use of microwave irradiation.
Po-Shen Pan, Fang-Rong Chang, Chia-Hung Lin, Hsien-Chi Chen, Yang-Chang Wu, Pin-Yi Liu, Chih-Cheng Chai   +6 more
doaj   +1 more source

Protection-Free Strategy for the Synthesis of Boro-Depsipeptides in Aqueous Media under Microwave-Assisted Conditions

Molecules, 2022
In this report, 19 boron-containing depsipeptides were synthesized via microwave-assisted Passerini three-component reaction (P-3CR) in an aqueous environment.
Shuo-Bei Qiu, Pei-Yao Liu, Bo-Cheng Wang, Pin-Rui Chen, Jing-Han Xiao, Ting-Yu Hsu, Kuan-Lin Pan, Zhi-Yin Lai, Yi-Wei Chen, Ying-Chuan Chen, Jen-Kun Chen, Po-Shen Pan   +11 more
doaj   +1 more source

Passerini Reactions on Biocatalytically Derived Chiral Azetidines [PDF]

Molecules, 2016
The purpose of this study was to explore a series of Passerini reactions on a biocatalytically derived enantiopure azetidine-2-carboxyaldehyde in order to obtain, in a diastereoselective manner, polyfunctionalised derivatives having the potential to be cyclized to chiral bridged bicyclic nitrogen heterocycles.
MONI, LISA, BANFI, LUCA, BASSO, ANDREA, Bozzano, A, SPALLAROSSA, MARTINA, Wessjohann, L., RIVA, RENATA   +6 more
openaire   +3 more sources

Stereochemical Control of the Passerini Reaction

, 2016
A catalytic asymmetric Passerini reaction using tridentate indan (pybox) Cu(II) Lewis acid complex 4 with substrates capable of bidentate coordination has been achieved.
Stuart L. Schreiber (189260), Peter R. Andreana (1590037), Chang C. Liu (1301685)   +2 more
core   +2 more sources

Pyrrolidinodiones in Enol-Ugi, Enol-Passerini, and Anomalous Enol-Passerini Condensations

Proceedings, 2019
In continuation of our recent research on the development of novel multicomponent reactions with isocyanides, we have used, for the first time, enols as the acid components in Ugi- and Passerini-type reactions. Thus, electron-poor pyrrolidinodiones react
Ana G. Neo, Carlos F. Marcos
doaj   +1 more source

Light‐Controlled Modulation of 15‐Lipoxygenase‐1 Regulates Intestinal Inflammatory Signaling

Angewandte Chemie, EarlyView.
The developed target‐guided strategy enables the rational design of diazo‐based photoswitchable inhibitors of 15‐lipoxygenase‐1. Distinct molecular architectures program opposite light‐dependent activity, allowing on‐demand control of enzyme inhibition.
Anastasia Louka, Eirini‐Eleni Kalaitzaki, Athanasios Panousis, Sotirios Bonoras, Charalampos Livas, George Froudakis, Ioannis Drygiannakis, Athina Damianaki, George Kolios, Vassilis Valatas, Nikolaos Eleftheriadis   +10 more
wiley   +2 more sources

Optimized Conditions for Passerini-Smiles Reactions and Applications to Benzoxazinone Syntheses

Molecules, 2016
Initial conditions disclosed for the Passerini-Smiles reaction are associated with a lack of efficiency that has prevented chemists from using it since its discovery.
Elodie Martinand-Lurin, Aurélie Dos Santos, Emmanuelle Robineau, Pascal Retailleau, Philippe Dauban, Laurence Grimaud, Laurent El Kaïm   +6 more
doaj   +1 more source