Results 241 to 250 of about 97,046 (344)

Recent applications of aminouracil in multicomponent reactions

, 2021
Ramin Javahershenas
openalex   +2 more sources

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Sequential pairwise reactions dictate phase evolution in the solid-state synthesis of multicomponent ceramics

, 2020
Akira Miura, Christopher J. Bartel, Yusuke Goto, Yoshikazu Mizuguchi, Chikako Moriyoshi, Yoshihiro Kuroiwa, Yongming Wang, Toshie Yaguchi, Manabu Shirai, Masanori Nagao, Nataly Carolina Rosero‐Navarro, Kiyoharu Tadanaga, Gerbrand Ceder, Wenhao Sun   +13 more
openalex   +1 more source

Synthesis and characterization of novel biheterocyclic compounds from 3‐alkoxy‐1H‐pyrazole‐4‐carbaldehydes via multicomponent reactions [PDF]

Viktorija Savickienė, Aurimas Bieliauskas, Sergey Belyakov, Algirdas Šačkus, Eglė Arbačiauskienė   +4 more
openalex   +1 more source

Quantitative Analysis Reveals Hitchhiking Drives Polysorbate Hydrolase Persistence Via Host Cell Protein–Antibody Interactions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier, Lukas Griesinger, Matthias Franzreb, Simon Kluters   +3 more
wiley   +1 more source

Access to Corrole-Appended Persubstituted Benzofurans by a Multicomponent Reaction: The Dual Role of p-Chloranil. [PDF]

Org Lett, 2020
Nowak-Król A, Koszarna B, Krzeszewski M, Lohrey TD, Arnold J, Gryko DT.   +5 more
europepmc   +1 more source

Exploring multicomponent reactions

, 2017
The nature of the starting materials allow multicomponent reactions to be versatile alternatives to classical chemical synthesis in the preparation of complex organic molecules or pharmaceutical products. The reason why multicomponent reactions have required so much attention is the fact that they have some advantages over classical chemical methods ...
openaire   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Development of recyclable Heterogeneous nano-catalysts for the green one-pot synthesis of Thiazole derivatives via multicomponent cyclization reaction

Akshay Patil, Brijadulal Ghosh
openalex   +1 more source

Amperometric enzyme biosensor for hydrogen peroxide via Ugi multicomponent reaction

, 2007
Conrado Camacho, Juan C. Matías, Daniel A. Garcı́a, Benjamin K. Simpson, Reynaldo Villalonga   +4 more
openalex   +2 more sources