Results 61 to 70 of about 2,406,837 (296)

Emerging crisis of multidrug-resistant enterococci from a rural tertiary care hospital of North India

Indian Journal of Health Sciences and Biomedical Research KLEU, 2021
INTRODUCTION: Enterococci are emerging as a major pathogen causing a variety of hospital-acquired nosocomial infections and community-acquired infections contributing significantly to patient's morbidity and mortality.
Jyoti Sangwan, Kirti Lohan, Pratibha Mane, Mukesh Kumar   +3 more
doaj   +1 more source

Role in routing to the plasma membrane of the L 0 domain of the multidrug resistance protein MRP1 [PDF]

, 2004
Die mehrfache Chemotherapieresistenz (Multidrug Resistance) beruht auf vermehrtem Transport von Xenobiotika aus der Zelle, was zu einer dramatischen Verringerung der intrazellulären Konzentration von chemotherapeutischen Substanzen führt.
Calenda, Giulia
core  

The prevalences of Salmonella Genomic Island 1 variants in human and animal Salmonella Typhimurium DT104 are distinguishable using a Bayesian approach [PDF]

, 2011
Throughout the 1990s, there was an epidemic of multidrug resistant Salmonella Typhimurium DT104 in both animals and humans in Scotland. The use of antimicrobials in agriculture is often cited as a major source of antimicrobial resistance in pathogenic ...
Matthew J Denwood, Reid, S W J, Derek J Brown, Daniel T Haydon, Mellor Dominic J., Mellor, D J, Louise Matthews, Alison E. Mather, Matthews, L., Reid Stuart W. J., Mather, A E, Haydon, D T, Derek J. Brown, Alison E Mather, John E Coia, Coia John E., Matthews, L, Mather, A.E., Stuart W J Reid, Daniel T. Haydon, Brown, D J, Denwood Matthew J., Haydon, D.T., Coia, J E, Dominic J. Mellor, Brown Derek J., John E. Coia, Coia, J.E., Reid, S.W.J., Matthew J. Denwood, Matthews Louise, Stuart W. J. Reid, Denwood, M.J., Denwood, M J, Mather Alison E., Mellor, D.J., Dominic J Mellor, Haydon Daniel T., Brown, D.J.   +38 more
core   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

Experimental Evolution of Multidrug Resistance in Neurospora crassa under Antifungal Azole Stress

Journal of Fungi, 2022
Multidrug resistance, defined as the resistance to multiple drugs in different categories, has been an increasing serious problem. Limited antifungal drugs and the rapid emergence of antifungal resistance prompt a thorough understanding of how the ...
Mi Zhou, Chengcheng Hu, Yajing Yin, Jingji Wang, Shuting Ye, Yifa Yu, Xianyun Sun, Shaojie Li   +7 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

The nucleotide binding domains of multidrug resistance-p-glycoproteins [PDF]

, 2001
Bibliography: leaves 116 ...
De Wet, Heidi
core   +1 more source

Identification and characterisation of a novel multidrug-resistant streptococcus, Streptococcus toyakuensis sp. nov., from a blood sample

Journal of Global Antimicrobial Resistance, 2022
: Objectives: In 2018, we isolated multidrug-resistant α-haemolytic streptococci TP1632 from the blood of a 34-year-old patient with bacteraemia. This study aimed to characterise α-haemolytic streptococci TP1632 and elucidate its multidrug resistance ...
Takeaki Wajima, Atsuya Hagimoto, Emi Tanaka, Yoshiaki Kawamura, Hidemasa Nakaminami   +4 more
doaj   +1 more source

Elucidation of the structure and molecular mechanism of the tripartite multidrug efflux pumps in the Gram-negative pathogens: Vibrio cholerae and Neisseria gonorrhoeae [PDF]

, 2006
In bacteria, multidrug efflux systems have been identified as significant determinants of resistance recently. These resistance pumps are widely distributed in bacterial species and many pathogenic bacteria posses them, which play an important role in ...
Du, Dijun
core  

Lipid bilayer composition influences small multidrug transporters [PDF]

, 2008
Background: Membrane proteins are influenced by their surrounding lipids. We investigate the effect of bilayer composition on the membrane transport activity of two members of the small multidrug resistance family; the Escherichia coli transporter, EmrE
Charalambous, K, Curnow, Paul, Curnow, P., Curnow, P, Miller, D, Charalambous, Kalypso, Booth, Paula J, Miller, D., Booth, P.J., Miller, David, Booth, PJ   +10 more
core   +1 more source