Results 71 to 80 of about 234,319 (307)

Detection approaches for multidrug resistance genes of leukemia

, 2017
Ying Du, Baoan Chen Department of Hematology and Oncology (Key Department of Jiangsu Medicine), School of Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu Province, People’s Republic of China Abstract: Leukemia is a clonal ...
Baoan Chen, Du Y, Ying Du, Chen B
core   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Characterisation of the vibrio cholerae antibiotic resistance var operon [PDF]

, 2007
The discovery and use of antibiotics in the chemotherapy of bacterial infections has revolutionised medicine as it is today. Unfortunately, the progressive use of antibiotics has promoted the evolution of bacterial defences against these mediators and ...
Massam-Wu, Teresa
core  

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

Advanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang, Yali Chang, Zibin Chu, Linghao Zhang, Tengfang Zhang, Dai Erhei, Xin Su, Zhe Yin   +7 more
wiley   +1 more source

Predictive factors for multidrug-resistant gram-negative bacteria among hospitalised patients with complicated urinary tract infections

Antimicrobial Resistance and Infection Control, 2018
Background Patients with complicated urinary tract infections (cUTIs) frequently receive broad-spectrum antibiotics. We aimed to determine the prevalence and predictive factors of multidrug-resistant gram-negative bacteria in patients with cUTI.
Aina Gomila, Evelyn Shaw, Jordi Carratalà, Leonard Leibovici, Cristian Tebé, Irith Wiegand, Laura Vallejo-Torres, Joan M. Vigo, Stephen Morris, Margaret Stoddart, Sally Grier, Christiane Vank, Nienke Cuperus, Leonard Van den Heuvel, Noa Eliakim-Raz, Cuong Vuong, Alasdair MacGowan, Ibironke Addy, Miquel Pujol, on behalf of COMBACTE-MAGNET WP5- RESCUING Study   +19 more
doaj   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Characterization of Posttranslationally Modified Multidrug Efflux Pumps Reveals an Unexpected Link between Glycosylation and Antimicrobial Resistance

mBio, 2020
The substantial rise in multidrug-resistant bacterial infections is a current global imperative. Cumulative efforts to characterize antimicrobial resistance in bacteria has demonstrated the spread of six families of multidrug efflux pumps, of which ...
Sherif Abouelhadid, John Raynes, Tam Bui, Jon Cuccui, Brendan W. Wren   +4 more
doaj   +1 more source

Microfluidic chip enables single-cell measurement for multidrug resistance in triple-negative breast cancer cells

, 2020
Aims: Triple-negative breast cancer patients are commonly treated with combination chemotherapy. Nonetheless, outcomes remain substandard with relapses being of a frequent occurrence.
Lopez, Jose Alejandro, Noghabi, Hamideh Sharifi, Li, PCH, Parekh, Karan, Noghabi, HS, Li, Paul Chi Hang, Parekh, K, Lopez, JA   +7 more
core   +1 more source

Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New Guinea [PDF]

, 2012
: BACKGROUND: Monitoring drug resistance in Mycobacterium tuberculosis is essential to curb the spread of tuberculosis (TB). Unfortunately, drug susceptibility testing is currently not available in Papua New Guinea (PNG) and that impairs TB control in ...
Gagneux, S., Siba Peter, Beck, H. P., Hans-Peter Beck, Beck Hans-Peter, Carter Robyn, Paul Harino, Harino, P., Carter, R., Serej Ley, Ley Serej, Siba, P., Gagneux Sebastien, Borrell Sonia, Coscolla Mireia, Mireia Coscolla, Ballif Marie, Stefan Niemann, Ley, S., Marie Ballif, Coulter, C., Robyn Carter, Coulter Christopher, Christopher Coulter, Ballif, M., Peter Siba, Niemann, S., Harino Paul, Niemann Stefan, Sebastien Gagneux, Phuanukoonnon, S., Borrell, S., Coscolla, M., Sonia Borrell, Suparat Phuanukoonnon, Phuanukoonnon Suparat   +35 more
core   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source