A multienzyme complex channels substrates and electrons through acetyl-CoA and methane biosynthesis pathways in Methanosarcina. [PDF]
PLoS One, 2014 Multienzyme complexes catalyze important metabolic reactions in many organisms, but little is known about the complexes involved in biological methane production (methanogenesis). A crosslinking-mass spectrometry (XL-MS) strategy was employed to identify
Lieber DJ +6 more
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Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta gene as a tumour suppressor in stomach adenocarcinoma. [PDF]
Front Oncol, 2022 BackgroundStomach adenocarcinoma (STAD) is the most common type of gastric cancer. In this study, the functions and potential mechanisms of hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta (HADHB) in STAD were explored ...
Li Y, Xiong JB, Jie ZG, Xiong H.
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Fine tuning of spatial arrangement of enzymes in a PCNA-mediated multienzyme complex using a rigid poly-L-proline linker. [PDF]
PLoS One, 2013 Inspired by natural multienzyme complexes, many types of artificial multienzyme complexes have recently been constructed. We previously constructed a self-assembled complex of a bacterial cytochrome P450 and its ferredoxin and ferredoxin reductase ...
Haga T, Hirakawa H, Nagamune T.
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A light-responsive multienzyme complex combining cascade enzymes within a peptide-based matrix. [PDF]
RSC Adv, 2018 In this study, a light-responsive multienzyme complex (GOx&hemin@PepM) was developed by incorporating glucose oxidase (GOx) and hemin within a peptide-based matrix.
Wang Y +6 more
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Regulation of Brain Pyruvate Dehydrogenase Multienzyme Complex [PDF]
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1978 SUMMARY:A number of excellent and comprehensive reviews on various aspects of pyruvate dehydrogenase multienzyme complex have been written recently. The purpose of the present review is to summarize briefly the reaction mechanism and the regulation of this enzyme. Emphasis is put on the most recent literature not covered by previous reviews. Particular
A. Barbeau, T.T. Ngo
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Effect of a multienzyme complex in wheat-soybean meal diet on digestibility of broiler chickens under different rearing conditions [PDF]
Italian Journal of Animal Science, 2010 This study investigated the effects of a multienzyme complex containing protease and carbohydrase enzymes on the performance and nutrient digestibility of broiler chickens under different rearing conditions from 1 to 42 d of age. Two experimental starter
Fuensanta Hernández +3 more
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Hypoxia drives the assembly of the multienzyme purinosome complex [PDF]
Journal of Biological Chemistry, 2020 The purinosome is a dynamic metabolic complex composed of enzymes responsible for de novo purine biosynthesis, whose formation has been associated with elevated purine demand.
Cyrielle Doigneaux +5 more
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Multienzyme complex for metabolic channeling in mammalian DNA replication. [PDF]
Proceedings of the National Academy of Sciences, 1980 In the DNA-synthesizing phase (S phase) of CHEF/18 Chinese hamster embryo fibroblast cells, six enzymes associated with DNA metabolism, including DNA polymerase (deoxynucleoside triphosphate:DNA deoxynucleotidyl-transferase, EC 2.7.7.7), were largely localized in the nuclear region (karyoplasts).
G. Prem Veer Reddy, Arthur B. Pardee
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Effects of Dietary Multienzyme Complex Supplementation on Growth Performance, Digestive Capacity, Histomorphology, Blood Metabolites and Hepatic Glycometabolism in Snakehead (Channa argus). [PDF]
Animals (Basel), 2022 The present study evaluated the impact of dietary multienzyme complex (MEC) supplementation on growth performance, digestive enzyme activity, histomorphology, serum metabolism and hepatopancreas glycometabolism in snakeheads (Channa argus).
Ding X +5 more
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Analysis of allosteric communication in a multienzyme complex by ancestral sequence reconstruction. [PDF]
Proc Natl Acad Sci U S A, 2020 Significance Enzyme complexes consist of several protein subunits that often catalyze sequential reactions in the cell. The activities of the individual subunits must be kept in phase, which requires a sophisticated communication mechanism that is ...
Schupfner M +4 more
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