Navigating the Complex Terrain of Methane Synthesis: Multienzyme Control Points and Data-Driven Strategies. [PDF]
ACS OmegaMohlomi N +4 more
europepmc +3 more sources
Adaptations in Protein Expression and Regulated Activity of Pyruvate Dehydrogenase Multienzyme Complex in Human Systolic Heart Failure. [PDF]
Oxid Med Cell Longev, 2019 Pyruvate dehydrogenase (PDH) complex, a multienzyme complex at the nexus of glycolytic and Krebs cycles, provides acetyl-CoA to the Krebs cycle and NADH to complex I thus supporting a critical role in mitochondrial energy production and cellular survival.
Sheeran FL +4 more
europepmc +2 more sources
First evidence for a multienzyme complex of lipid biosynthesis pathway enzymes in Cunninghamella bainieri. [PDF]
Sci Rep, 2018 Malic enzyme (ME) plays a vital role in determining the extent of lipid accumulation in oleaginous fungi being the major provider of NADPH for the activity of fatty acid synthase (FAS).
Shuib S +4 more
europepmc +2 more sources
Evaluation of the Safety and Efficacy of a Multienzyme Complex in Patients with Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study. [PDF]
J Med Food, 2018 Functional dyspepsia (FD) is a highly prevalent disorder having nonspecific symptoms and varied pathophysiology. Its treatment remains a challenge as therapeutic options are limited, unsatisfactory, and elusive.
Majeed M +6 more
europepmc +2 more sources
Molecular characterization of hypothetical scaffolding-like protein S1 in multienzyme complex produced by Paenibacillus curdlanolyticus B-6. [PDF]
AMB Express, 2019 Paenibacillus curdlanolyticus B-6 produces an extracellular multienzyme complex containing a hypothetical scaffolding-like protein and several xylanases and cellulases. The largest (280-kDa) component protein, called S1, has cellulose-binding ability and
Pason P +6 more
europepmc +2 more sources
NAC guides a ribosomal multienzyme complex for nascent protein processing. [PDF]
NatureLentzsch AM +8 more
europepmc +2 more sources
A multipronged approach unravels unprecedented protein-protein interactions in the human 2-oxoglutarate dehydrogenase multienzyme complex. [PDF]
J Biol Chem, 2018 The human 2-oxoglutaric acid dehydrogenase complex (hOGDHc) plays a pivotal role in the tricarboxylic acid (TCA) cycle, and its diminished activity is associated with neurodegenerative diseases. The hOGDHc comprises three components, hE1o, hE2o, and hE3,
Zhou J +10 more
europepmc +2 more sources
Comparison study between single enzyme and multienzyme complex in distiller's dred grains with soluble supplemented diet in broiler chicken. [PDF]
J Anim Sci TechnolUpregulation of the nutritional value of feed is the major target of various studies in the livestock industry, and dietary enzyme supplementation could aid in digesting the nondegrading nutrients of grains in feed ingredients.
Kwak MJ +5 more
europepmc +2 more sources
Active site coupling in multienzyme complexes [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2005 René A. W. Frank +4 more
openaire +3 more sources