Background Efficient biotechnological conversion of lignocellulosic biomass to valuable products, such as transportation biofuels, is ecologically attractive, yet requires substantially improved mechanistic understanding and optimization to become ...
Zhenxing Ren +4 more
doaj +1 more source
The Role of One‐Carbon Metabolism in Cancer and Its Therapeutic Significance
One‐Carbon metabolism in T‐cell activation and tumor competition. T‐cell activation shifts metabolic pathways, promoting anabolic metabolism and bioenergetic capacity. One‐carbon metabolism plays a crucial role in histone and DNA methylation in activated T cells.
Yuting Jiang +3 more
wiley +1 more source
Interferon y Stimulation Modulates the Proteolytic Activity and Cleavage Site Preference of 20S Mouse Proteasomes [PDF]
The proteasome is a 700-kD multisubunit enzyme complex with several proteolytically active sites. The enzyme complex is involved in both ubiquitin-dependent and -independent protein degradation and may contribute to the processing of antigens presented ...
Boes, Bettina +5 more
core
Enhancement of cellulosome-mediated deconstruction of cellulose by improving enzyme thermostability [PDF]
Background: The concerted action of three complementary cellulases from Clostridium thermocellum, engineered to be stable at elevated temperatures, was examined on a cellulosic substrate and compared to that of the wild-type enzymes. Exoglucanase Cel48S
Arnold, Frances H. +9 more
core +2 more sources
Processive Enzymes Kept on a Leash: How Cellulase Activity in Multienzyme Complexes Directs Nanoscale Deconstruction of Cellulose. [PDF]
Zajki-Zechmeister K +4 more
europepmc +1 more source
ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak +7 more
wiley +1 more source
Adaptor Scaffoldins: An Original Strategy for Extended Designer Cellulosomes, Inspired from Nature
Designer cellulosomes consist of chimeric cohesin-bearing scaffoldins for the controlled incorporation of recombinant dockerin-containing enzymes. The largest designer cellulosome reported to date is a chimeric scaffoldin that contains 6 cohesins.
Johanna Stern +3 more
doaj +1 more source
SsPDHX affects acetyl‐CoA and ATP metabolism and is required for normal growth, development, and pathogenicity of S. sclerotiorum. SIGS or HIGS targeting Sspdhx enhances host resistance to Sclerotinia disease. ABSTRACT Sclerotinia sclerotiorum is a destructive pathogen with a broad host range, long‐term soil survival, and is difficult to control ...
Qingna Shang +14 more
wiley +1 more source
Deconstruction of Lignocellulose into Soluble Sugars by Native and Designer Cellulosomes
Lignocellulosic biomass, the most abundant polymer on Earth, is typically composed of three major constituents: cellulose, hemicellulose, and lignin. The crystallinity of cellulose, hydrophobicity of lignin, and encapsulation of cellulose by the lignin ...
Sarah Moraïs +8 more
doaj +1 more source
Investigations in space-related molecular biology, including considerations of the molecular organization of extraterrestrial matter Technical progress report [PDF]
Space related molecular biology and molecular organization of extraterrestrial matter - design and construction of high vacuum container for transfer of extraterrestrial collecting ...
Fernandez-Moran, H.
core +1 more source

