The P450 multigene family of Fontainea and insights into diterpenoid synthesis [PDF]
Background Cytochrome P450s (P450s) are enzymes that play critical roles in the biosynthesis of physiologically important compounds across all organisms. Although they have been characterised in a large number of plant species, no information relating to
Shahida A. Mitu+5 more
doaj +2 more sources
The dirigent multigene family in Isatis indigotica: gene discovery and differential transcript abundance. [PDF]
BackgroundIsatis indigotica Fort. is one of the most commonly used traditional Chinese medicines. Its antiviral compound is a kind of lignan, which is formed with the action of dirigent proteins (DIR).
Li Q+5 more
europepmc +2 more sources
Olfactory receptor multigene family in vertebrates: from the viewpoint of evolutionary genomics. [PDF]
Olfaction is essential for the survival of animals. Diverse odor molecules in the environment are detected by the olfactory receptors (ORs) in the olfactory epithelium of the nasal cavity. There are ~400 and ~1,000 OR genes in the human and mouse genomes,
Niimura Y.
europepmc +2 more sources
Predicted expansion of the claudin multigene family
Claudins (Cldn) are essential membrane proteins of tight junctions (TJs), which form the paracellular permselective barrier. They are produced by a multi-gene family of 24 reported members in mouse and human. Based on a comprehensive search combined with phylogenetic analyses, we identified three novel claudins (claudin-25, -26, and -27).
Katsuhiko Mineta+10 more
semanticscholar +4 more sources
Conserved pattern-based classification of human odorant receptor multigene family [PDF]
Conserved protein-coding sequences are critical for maintaining protein function across species. Odorant receptors (ORs), a large poorly understood multigene family responsible for odor detection, lack comprehensive classification methods that reflect ...
Sang Eun Ryu+5 more
doaj +2 more sources
Molecular evolution of the primate α-/θ-defensin multigene family. [PDF]
The primate α-/θ-defensin multigene family encodes versatile endogenous cationic and amphipathic peptides that have broad-spectrum antibacterial, antifungal and antiviral activity.
Dong-Qiang Cheng+2 more
doaj +2 more sources
Clues to evolution of the SERA multigene family in 18 Plasmodium species. [PDF]
SERA gene sequences were newly determined from 11 primate Plasmodium species including two human parasites, P. ovale and P. malariae, and the evolutionary history of SERA genes was analyzed together with 7 known species.
Arisue N+7 more
europepmc +2 more sources
Kallikrein Multigene Families and the Regulation of Their Expression
Tissue kallikreins are a group of closely related serine proteinases that are represented by multigene families in mice and rats. The existence of similar, large, kallikrein-like gene families in other mammalian species is currently a matter of dispute.
Stephen R. Murray+3 more
openalex +4 more sources
Multigene Family of Pore-Forming Toxins from Sea Anemone Heteractis crispa [PDF]
Sea anemones produce pore-forming toxins, actinoporins, which are interesting as tools for cytoplasmic membranes study, as well as being potential therapeutic agents for cancer therapy.
Elena Leychenko+7 more
doaj +2 more sources
A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
Linda B. Buck, Richard Axel
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