Results 41 to 50 of about 42,962 (201)

Accessing the Variability of Multicopy Genes in Complex Genomes using Unassembled Next-Generation Sequencing Reads: The Case of Trypanosoma cruzi Multigene Families

mBio, 2022
Repetitive elements cause assembly fragmentation in complex eukaryotic genomes, limiting the study of their variability. The genome of Trypanosoma cruzi, the parasite that causes Chagas disease, has a high repetitive content, including multigene families.
João Luís Reis-Cunha, Anderson Coqueiro-dos-Santos, Samuel Alexandre Pimenta-Carvalho, Larissa Pinheiro Marques, Gabriela F. Rodrigues-Luiz, Rodrigo P. Baptista, Laila Viana de Almeida, Nathan Ravi Medeiros Honorato, Francisco Pereira Lobo, Vanessa Gomes Fraga, Lucia Maria da Cunha Galvão, Lilian Lacerda Bueno, Ricardo Toshio Fujiwara, Mariana Santos Cardoso, Gustavo Coutinho Cerqueira, Daniella C. Bartholomeu   +15 more
doaj   +1 more source

Evolutionary dynamics of olfactory receptor genes in chordates: interaction between environments and genomic contents

Human Genomics, 2009
Olfaction is essential for the survival of animals. Versatile odour molecules in the environment are received by olfactory receptors (ORs), which form the largest multigene family in vertebrates. Identification of the entire repertories of OR genes using
Niimura Yoshihito
doaj   +1 more source

Identification of the novel evolutionary conserved obstructor multigene family in invertebrates

, 2005
Insects have evolved chitin-containing structures such as the cuticle or peritrophic membranes that serve to protect their bodies against the hostile environment. The specific mechanisms by which these structures are produced, are mostly unknown. We have
Matthias Behr, Behr, Matthias, Hoch, Michael, Michael Hoch   +3 more
core   +1 more source

Genome-Wide Analysis of the Class III Peroxidase Gene Family in Physcomitrium patens and a Search for Clues to Ancient Class III Peroxidase Functions

International Journal of Plant Biology
Plant class III peroxidases (PRXs) catalyze generation of reactive oxygen species and oxidation of various compounds including lignin precursors. PRXs function in cell wall metabolism, defense, and stress responses. However, gene redundancy and catalytic
Vincent P. M. Aparato, Fazle Rabbi, Taylor Madarash, Wyllie A. Brisbourne, Elizabeth I. Barker, Dae-Yeon Suh   +5 more
doaj   +1 more source

Molecular analyses of a barley multigene family homologous to the yeast protein kinase gene SNF1

, 1992
Genomic sequences homologous to the yeast gene SNF1 have been isolated from barley (Hordeum vulgare) cv. Sunbar. SNF1 encodes a protein serine/threonine kinase required for the derepression of a number of genes, including SUC2 (invertase) in response to ...
Kreis, M., Vicentecarbajosa, J., Hannappel, U., Martin Kreis, Jesus Vicente-Carbajosa, Halford, N. G., Paolo A. Sabelli, Sabelli, P. A., Shewry, P. R., Ulrich Hannappel, Nigel G. Halford, Peter R. Shewry   +11 more
core   +1 more source

First identified Korean family with Tatton-Brown-Rahman Syndrome caused by the novel variant c.118G>C p.(Glu40Gln) [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2019
Tatton-Brown-Rahman Syndrome (TBRS), an overgrowth syndrome caused by heterozygous mutation of DNMT3A, first was described in 2014. Approximately 60 DNMT3A variants, including 32 missense variants, have been reported, with most missense mutations located
Cha Gon Lee, Ja-Hyun Jang, Ji-Young Seo
doaj   +1 more source

Expression of members of the Saccharomyces cerevisiae hsp70 multigene family

, 1989
The hsp70 multigene family of Saccharomyces cerevisiae is a complex multigene family, composed of members exhibiting complex patterns of regulation.
Elizabeth A. Craig, Margaret Werner-Washburne   +1 more
core   +1 more source

Anaplasma marginale major surface protein 3 is encoded by a polymorphic, multigene family

, 1997
The immunodominant surface protein, MSP3, is structurally and antigenically polymorphic among strains of Anaplasma marginale. In this study we show that a polymorphic multigene family is at least partially responsible for the variation seen in MSP3.
Alleman, A R, Palmer, G H, Perryman, L E, Barbet, A F, McElwain, T F, McGuire, T C   +5 more
core   +1 more source

A wheat gene TaSAP17-D encoding an AN1/AN1 zinc finger protein improves salt stress tolerance in transgenic Arabidopsis

Journal of Integrative Agriculture, 2018
The stress-associated protein (SAP) multigene family is conserved in both animals and plants. Its function in some animals and plants are known, but it is yet to be deciphered in wheat (Triticum aestivum L.).
Qiao-fang XU, Xin-guo MAO, Yi-xue WANG, Jing-yi WANG, Ya-jun XI, Rui-lian JING   +5 more
doaj   +1 more source

CRISPR Interference of a Clonally Variant GC-Rich Noncoding RNA Family Leads to General Repression of var Genes in Plasmodium falciparum

mBio, 2020
The human malaria parasite Plasmodium falciparum uses mutually exclusive expression of the PfEMP1-encoding var gene family to evade the host immune system. Despite progress in the molecular understanding of the default silencing mechanism, the activation
Anna Barcons-Simon, Carlos Cordon-Obras, Julien Guizetti, Jessica M. Bryant, Artur Scherf   +4 more
doaj   +1 more source