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Murine Hox Genes — A Multigene Family
1988The embryonal development of higher organisms is conducted by a network of many different structural and regulatory gene functions whose complexity is yet poorly understood. Some genetic elements identified as being involved in specifying segment identity of the fruit fly Drosophila melanogaster are the homeotic genes (Ouweneel 1976).
Fibi, M., Kessel, M., Gruss, P.
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The α-amylase multigene family
Trends in Plant Science, 1997Many α-amylase genes have been cloned from various cereals, and sequence analysis reveals that these fall into two major classes and three subfamilies. In parallel studies, many α-amylase isoforms have been characterized and their corresponding genes identified.
Toshiaki Mitsui, Kimiko Itoh
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The Actin and Myosin Multigene Families
1985The Actin and Myosin Multigene Families: a) a study of the accumulation of their RNA transcripts demonstrates different developmental strategies during skeletal muscle formation, b) a genetic analysis of their chromosomal organization indicates gene dispersion and permits some precise localizations on the genetic map of the mouse.
M, Buckingham +8 more
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On the evolution of multigene families
Theoretical Population Biology, 1983Multigene families are classified into three groups: small families as exemplified by hemoglobin genes of mammals; middlesize multigene families, by genes of mammalian histocompatibility antigens; and large multigene families, by variable region genes of immunoglobulins. Facts and theories on these evolving multigene families are reviewed, with special
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Malaria Multigene Families: The Price of Chronicity
Parasitology Today, 2000In this article, Georges Snounou, William Jarra and Peter Preiser discuss the survival strategy of malaria parasites in the light of a novel mechanism of clonal phenotypic variation recently described for a multigene family of Plasmodium yoelii yoelii.
G, Snounou, W, Jarra, P R, Preiser
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The plant multigenic family of thiol peroxidases
Free Radical Biology and Medicine, 2005Thiol peroxidases are ubiquitous recently characterized heme-free peroxidases, which catalyze the reduction of peroxynitrites and of various peroxides by catalytic cysteine residues and thiol-containing proteins as reductants. In plants, five different classes can be distinguished, according to the number and the position of conserved catalytic ...
Rouhier, Nicolas, Jacquot, J.P.
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The HSP70 multigene family of Caenorhabditis elegans
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 19901. The heat shock response of the nematode Caenorhabditis elegans has been characterized. 2. There are at least nine genes in the hsp70 multigene family of C. elegans. 3. Five of the hsp70 genes have been characterized and assigned to one of at least three hsp70 gene subfamilies.
M F, Heschl, D L, Baillie
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Multigene families in African swine fever virus: family 110
Journal of Virology, 1990The genome of African swine fever virus was screened for the existence of repetitive sequences by hybridization between different cloned restriction fragments covering the viral DNA. Several sets of repeated sequences were detected in fragments located close to the DNA ends.
J M, Almendral +3 more
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Automatic multigenic family annotation: risks and solutions
Trends in Genetics, 2014A major challenge facing bioinformatics today is the efficient annotation of the exponential flow of genomic data. This has led to an increasing dependence on automatic annotation procedures, despite the relatively high error rates of these programs, particularly for multigenic families.
Nizar, Fawal +3 more
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Adaptive evolution of animal toxin multigene families
Gene, 2000Animal toxins comprise a diverse array of proteins that have a variety of biochemical and pharmacological functions. A large number of animal toxins are encoded by multigene families. From studies of several toxin multigene families at the gene level the picture is emerging that most have been functionally diversified by gene duplication and adaptive ...
D, Kordis, F, Gubensek
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