Results 141 to 150 of about 32,835 (232)

Evaluating Multimerization of Apoptin Homologs

, 2015
PCV1 VP3, is homologous to Apoptin. Apoptin is known to self-multimerize and induce apoptosis in cancerous cells. Due to their similarities, it is important to determine if multimerization is a crucial component in the apoptosis. To investigate this, GFP
Bebrin, Nicole Emily, Konicki, ErinMari
core  

Demonstration of a Simple Epitope Tag Multimerization Strategy for Enhancing the Sensitivity of Protein Detection Using Drosophila vAChT

G3: Genes, Genomes, Genetics, 2020
Kole V. Tison, Hannah M. McKinney, R. Steven Stowers   +2 more
doaj   +1 more source

Interfering with multimerization of netrin-1 receptors triggers tumor cell death.

, 2009
International audienceNetrin-1 was recently proposed to control tumorigenesis by inhibiting apoptosis induced by the dependence receptors DCC (Deleted in colorectal cancer) and UNC5H.
D E Bredesen, C Guix, F Llambi, Mehlen, Patrick, Delloye-Bourgeois, C, Guenebeaud, C, Bredesen, Dale, E., Mille, Frédéric, Guix, Catherine, Castro-Obregon, Susana, S Castro-Obregon, Mehlen, P, C Guenebeaud, Guenebeaud, Céline, Thibert, Chantal, Mille, F, Bredesen, D, Llambi, Fabien, C Delloye-Bourgeois, F Mille, Guix, C, Castro-Obregon, S, C Thibert, Delloye-Bourgeois, Céline, Llambi, F, P Mehlen   +25 more
core   +1 more source

Optimizing the Multimerization Properties of Quinoline-Based Allosteric HIV-1 Integrase Inhibitors

Viruses
Allosteric HIV-1 Integrase (IN) Inhibitors or ALLINIs bind at the dimer interface of the IN, away from the enzymatic catalytic site, and disable viral replication by inducing over-multimerization of IN.
Jian Sun, Jacques J. Kessl
doaj   +1 more source

Adipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis

, 2014
The physiological role of the spliced form of X-box–binding protein 1 (XBP1s), a key transcription factor of the endoplasmic reticulum (ER) stress response, in adipose tissue remains largely unknown.
Kersten, A.H., Xia, S., Liu, M., Liu, Y., Qi, L., Yang, L., Sha, H., Liu, F.   +7 more
core   +1 more source

Is HIV-1 Gag and Gag-Pol multimerization initiated during protein translation?

, 2000
Is HIV-1 Gag and Gag-Pol multimerization initiated during protein ...
S Crowe (13428231), D Harrich (13719703), W Hooker (13719700), M Hill (7674827), Johnson Mak (13082904)   +4 more
core  

ASPPs multimerize protein phosphatase 1

Abstract Protein Phosphatase 1 (PP1) activity is thought to be spatiotemporally defined by hundreds of different regulatory subunits, but their mechanisms of action are largely unknown. The Ankyrin repeat, SH3-domain, and Proline-rich region containing Proteins (ASPPs) bind and localize PP1 to cell-cell junctions ...
Derek T. Wei, Kayleigh N. Morrison, Gwendolyn M. Beacham, Erika Beyrent, Ying Zhang, Laurence Florens, Gunther Hollopeter   +6 more
openaire   +2 more sources

HIV-1 Integrase Multimerization By Quinoline Based Drugs

, 2019
Human Immunodeficiency Virus Type 1 (HIV-1), a single stranded RNA retrovirus, affects over 30,000,000 people world-wide1. The virus works by infecting and promoting destruction of CD4 immune cells.
Beauti, Samer
core  

Split Reporter Systems in Viral Protein-Protein Interactions and Multimerization: Mechanisms and Applications. [PDF]

Cells
Ahmad H, Masood F, Iqbal U, Shaltout M, Yukselten Y, Sutton RE.   +5 more
europepmc   +1 more source

VGLL4-driven TEAD4 multimerization orchestrates DNA binding and YAP recruitment. [PDF]

Nat Commun
Ren Z, Zhao Y, Yu W, Zhang X, Song X, Bao Y, Hu M, Chen L, Yang H, Cheng B, Liu C, Jin Y, Zhang L, Sun B.   +13 more
europepmc   +1 more source