Results 71 to 80 of about 1,322,987 (378)

Firefly Algorithms for Multimodal Optimization [PDF]

Symposium on Stochastic Algorithms: Foundations and Applications, 2009
Nature-inspired algorithms are among the most powerful algorithms for optimization. This paper intends to provide a detailed description of a new Firefly Algorithm (FA) for multimodal optimization applications.
Xin-She Yang
semanticscholar   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

In situ and in vitro cryo-EM reveal structures of mycobacterial encapsulin assembly intermediates

Communications Biology
Prokaryotes rely on proteinaceous compartments such as encapsulin to isolate harmful reactions. Encapsulin are widely expressed by bacteria, including the Mycobacteriaceae, which include the human pathogens Mycobacterium tuberculosis and Mycobacterium ...
Casper Berger, Chris Lewis, Ye Gao, Kèvin Knoops, Carmen López-Iglesias, Peter J. Peters, Raimond B. G. Ravelli   +6 more
doaj   +1 more source

Integrative prediction of gene expression with chromatin accessibility and conformation data

Epigenetics & Chromatin, 2020
Background Enhancers play a fundamental role in orchestrating cell state and development. Although several methods have been developed to identify enhancers, linking them to their target genes is still an open problem. Several theories have been proposed
Florian Schmidt, Fabian Kern, Marcel H. Schulz   +2 more
doaj   +1 more source

Tensor Fusion Network for Multimodal Sentiment Analysis

, 2017
Multimodal sentiment analysis is an increasingly popular research area, which extends the conventional language-based definition of sentiment analysis to a multimodal setup where other relevant modalities accompany language.
Cambria, Erik, Chen, Minghai, Morency, Louis-Philippe, Poria, Soujanya, Zadeh, Amir   +4 more
core   +1 more source

Eyes Wide Shut? Exploring the Visual Shortcomings of Multimodal LLMs [PDF]

Computer Vision and Pattern Recognition
Is vision good enough for language? Recent advancements in multimodal models primarily stem from the powerful reasoning abilities of large language models (LLMs).
Shengbang Tong, Zhuang Liu, Yuexiang Zhai, Yi Ma, Yann LeCun, Saining Xie   +5 more
semanticscholar   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Original Research. Transluminal Contrast Attenuation Gradient Is Associated with Coronary Plaque Vulnerability — a Computed Tomography Angiography-based Study

Journal of Cardiovascular Emergencies, 2017
The aim of this study was to demonstrate that the transluminal contrast attenuation gradient (TAG), a new CT imaging-derived marker of functional significance of a coronary stenosis, is directly associated with the vulnerability degree of atheromatous ...
Orzan Marius, Hodas Roxana, Dobra Mihaela, Rat Nora, Chitu Monica, Benedek Imre   +5 more
doaj   +1 more source

Structural Analysis of the Partially Disordered Protein EspK from Mycobacterium Tuberculosis

Crystals, 2020
For centuries, tuberculosis has been a worldwide burden for human health, and gaps in our understanding of its pathogenesis have hampered the development of new treatments.
Abril Gijsbers, Nuria Sánchez-Puig, Ye Gao, Peter J. Peters, Raimond B. G. Ravelli, Dritan Siliqi   +5 more
doaj   +1 more source