Results 61 to 70 of about 311,063 (257)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Multimodal precision MRI of the individual human brain at ultra-high fields

Scientific Data
Multimodal neuroimaging, in particular magnetic resonance imaging (MRI), allows for non-invasive examination of human brain structure and function across multiple scales.
Donna Gift Cabalo, Ilana Ruth Leppert, Risavarshni Thevakumaran, Jordan DeKraker, Youngeun Hwang, Jessica Royer, Valeria Kebets, Shahin Tavakol, Yezhou Wang, Yigu Zhou, Oualid Benkarim, Nicole Eichert, Casey Paquola, Julien Doyon, Christine Lucas Tardif, David Rudko, Jonathan Smallwood, Raul Rodriguez-Cruces, Boris C. Bernhardt   +18 more
doaj   +1 more source

Structural Analysis of the Partially Disordered Protein EspK from Mycobacterium Tuberculosis

Crystals, 2020
For centuries, tuberculosis has been a worldwide burden for human health, and gaps in our understanding of its pathogenesis have hampered the development of new treatments.
Abril Gijsbers, Nuria Sánchez-Puig, Ye Gao, Peter J. Peters, Raimond B. G. Ravelli, Dritan Siliqi   +5 more
doaj   +1 more source

Multimodal biometrics score level fusion using non-confidence information [PDF]

, 2011
Multimodal biometrics refers to automatic authentication methods that depend on multiple modalities of measurable physical characteristics. It alleviates most of the restrictions of single biometrics.
Chaw Poh, C
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Multimodal Entity Tagging with Multimodal Knowledge Base

CoRR, 2021
11 pages, 4 ...
Hao Peng 0015, Hang Li, Lei Hou 0001, Juanzi Li, Chao Qiao   +4 more
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

PSATM: Planar Structure Awareness-Based Texture Mapping for 3D Reconstruction of Photovoltaic Scenes

Computers
In the field of 3D reconstruction for photovoltaic scenes, current texture mapping techniques frequently encounter significant texture segmentation and apparent joins in uniform plane regions, such as solar panels, because they lack geometric structural ...
Mingwei Cao, Zilong Wang, Ning Li, Haifeng Zhao   +3 more
doaj   +1 more source

Multimodal virtual reality versus printed medium in visualization for blind people [PDF]

, 2002
In this paper, we describe a study comparing the strengths of a multimodal Virtual Reality (VR) interface against traditional tactile diagrams in conveying information to visually impaired and blind people. The multimodal VR interface consists of a force
Wai Yu, Yu, W., Brewster, S.A., Stephen Brewster   +3 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source