Results 81 to 90 of about 84,209 (281)

Multimorbidity in Older Adults [PDF]

open access: yesEpidemiologic Reviews, 2013
Multimorbidity, the coexistence of 2 or more chronic conditions, has become prevalent among older adults as mortality rates have declined and the population has aged. We examined population-based administrative claims data indicating specific health service delivery to nearly 31 million Medicare fee-for-service beneficiaries for 15 prevalent chronic ...
openaire   +2 more sources

Rehabilitation: The health strategy of the 21st century. [PDF]

open access: yes, 2017
There is strong evidence that population ageing and the epidemiological transition to a higher incidence of chronic, non-communicable diseases will continue to profoundly impact societies worldwide, putting more pressure on healthcare systems to respond ...
Bickenbach, Jerome   +3 more
core   +4 more sources

Prevalence and impact of prescribing cascades in community‐dwelling adults: Longitudinal analysis of the Irish longitudinal study on ageing (TILDA)

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Prescribing cascades occur when medication is prescribed to prevent/treat the adverse effects of another medication and may be intentional/unintentional. This study examines the prevalence of nine prescribing cascades (ThinkCascades) in The Irish Longitudinal StuDy on Ageing (TILDA).
Ann Sinéad Doherty   +7 more
wiley   +1 more source

APOE genotype and the effect of statins on lipid outcomes: A meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim APOE genotype may affect statin therapy response. We conducted a meta‐analysis to update and quantify this association across various outcomes. Methods We searched seven databases (MEDLINE, Scopus, Web of Science, the Cochrane Library, APA PsycINFO, CINAHL Plus and ClinicalTrials.gov) on 9 May 2024.
Innocent G. Asiimwe   +4 more
wiley   +1 more source

Multimorbidity and animal models

open access: yesAnimal Models and Experimental Medicine
Multimorbidity—the co‐occurrence of more than two chronic conditions in the same individual—is associated with premature death, diminished function, reduced quality of life, and increased societal burden.
Xinpei Wang   +7 more
doaj   +1 more source

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres   +8 more
wiley   +1 more source

Guidelines in the era of realistic medicine [PDF]

open access: yes, 2016
No abstract ...
James, R., Kinsella, J.
core   +1 more source

The extent and burden of high multimorbidity on older adults in the US: a descriptive analysis of Medicare beneficiaries

open access: yesBMC Geriatrics
Background The impact of multimorbidity (≥ 2 chronic diseases) on the well-being of older adults is substantial but variable. The burden of multimorbidity varies by the number and kinds of conditions, and timing of onset.
David A. Dorr   +7 more
doaj   +1 more source

Multimorbidity and co-morbidity in atrial fibrillation and effects on survival: findings from UK Biobank cohort [PDF]

open access: yes, 2017
Aims: To examine the number and type of co-morbid long-term health conditions (LTCs) and their associations with all-cause mortality in an atrial fibrillation (AF) population.
Connelly, Derek T.   +7 more
core   +1 more source

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