Results 91 to 100 of about 429,194 (230)

Preoperative Breast MRI and Histopathology in Breast Cancer: Concordance, Challenges and Emerging Role of CEM and mpMRI

Diagnostics
Background: Preoperative breast MRI is widely used in surgical planning because of its high sensitivity. However, discrepancies with histopathology remain common and can affect tumor size assessment and treatment decisions.
Aikaterini-Gavriela Giannakaki, Maria-Nektaria Giannakaki, Dimitris Baroutis, Sophia Koura, Eftychia Papachatzopoulou, Spyridon Marinopoulos, Georgios Daskalakis, Constantine Dimitrakakis   +7 more
doaj   +1 more source

Sensing‐Integrated Patient‐Derived Tumorspheres Predict Chemotherapeutic Efficacy via Local Extracellular pH Dynamics

Small, EarlyView.
The study introduces a 3D sensing‐integrated platform enabling real‐time, non‐invasive monitoring of pH dynamics in patient‐derived PDAC tumorspheres. It revealed distinct extracellular acidification patterns under FOLFIRINOX, gemcitabine, and paclitaxel, correlating with therapeutic efficacy.
Stefania Forciniti, Valentina Onesto, Anna Chiara Siciliano, Helena Iuele, Stefano D'Ugo, Norma Depalma, Cinzia Fasano, Alessandro D'Amuri, Giuseppe Gigli, Marcello G. Spampinato, Loretta L. del Mercato   +10 more
wiley   +1 more source

Multiparametric-MRI in diagnosis of prostate cancer

, 2015
Multiparametric-magnetic resonance imaging (mp-MRI) has shown promising results in diagnosis, localization, risk stratification and staging of clinically significant prostate cancer.
Masoom A Haider, Sangeet Ghai
core   +1 more source

Novel reference gene microseminoprotein‐beta based prostate cancer antigen 3 urine test: Enhanced diagnostic performance for prostate cancer and feasibility of non‐digital rectal examination urine sampling

UroPrecision, EarlyView.
Abstract Background The diagnosis of prostate cancer (PCa) is limited by low specificity and invasiveness. This study aims to establish a highly accurate, noninvasive reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR)‐based urinary prostate cancer antigen 3 (PCA3) assay system and explore the feasibility of using first‐morning urine
Jianglei Xu, Lu Yang, Cong Shi, Yiwei Jiang, Jing Chen, Xiaoxiao Sun, Xuejuan Gao, Xian Wang, Jianzhong Jiang, Xiuzhi Duan, Xuchu Wang, Yiyi Xie, Zhixian Yu, Zhihua Tao, Xiaobing Dou, Chunyu Jin   +15 more
wiley   +1 more source

Diagnostic Accuracy of 68Ga-PSMA-11 PET/MRI Compared with Multiparametric MRI in the Detection of Prostate Cancer. [PDF]

, 2018
Purpose To compare the diagnostic accuracy of gallium 68 (68Ga)-labeled prostate-specific membrane antigen (PSMA)-11 PET/MRI with that of multiparametric MRI in the detection of prostate cancer. Materials and Methods The authors performed a retrospective
Westphalen, Antonio C, Greene, Kirsten L, Hope, Thomas A, Nguyen, Hao G, Zhang, Li, Simko, Jeffry P, Carroll, Peter R, Hicks, Robert M   +7 more
core   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Multiparametric MRI in Prostate Cancer Diagnosis and Management

, 2021
© 2021 Thomas Ian Whish-WilsonProstate canceris the most common cancer affecting men in Australia. Detection has previously relied upon clinical examination and prostate specific antigen (PSA) screening.
Whish-Wilson, Thomas Ian
core   +1 more source

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

VIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan, Kathirvel Ayyaswamy, Parthasarathy Vellaichamy, Nagarajan Deivanayagam Pillai, Rithik Gobinath   +4 more
wiley   +1 more source

Development and validation of an interpretable ensemble model for predicting androgen receptor status in triple-negative breast cancer: a multi-center study

Frontiers in Oncology
PurposeReliable assessment of androgen receptor (AR) status in triple-negative breast cancer (TNBC) is critical for targeted therapy but remains challenging due to biopsy limitations from intratumoral heterogeneity.
Mei Ruan, Lixiu Cao, Yongliang Liu, Yanna Shan, Zhi Li, Chang Shao, Wen Xu   +6 more
doaj   +1 more source

Empty Versus Full Bladder Protocols in Radiotherapy Planning for Localised Prostate Cancer: A Dosimetric Study

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Background When planning prostate radiotherapy, full bladder preparation is widely used to displace bowel and bladder from high‐dose regions but is difficult to reproduce and can prolong workflows. Methods Twenty men with localised prostate cancer ± seminal vesicles underwent CT simulation with full and empty bladders.
Rebecca Louise Nield, Sagar Ramani, David Robert Harry Christie, Ingrid Lois Trono   +3 more
wiley   +1 more source