Results 111 to 120 of about 429,194 (230)

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Tumor classification and prediction using robust multivariate clustering of multiparametric MRI [PDF]

, 2015
International audienceIn neuro-oncology, the use of multiparametric MRI may better characterize brain tumor heterogeneity. To fully exploit multiparametric MRI (e.g. tumor classification), appropriate analysis methods are yet to be developed.
Lemasson, Benjamin, Arnaud, Alexis, Forbes, Florence, Barbier, Emmanuel Luc   +3 more
core   +1 more source

A large model for non-invasive and personalized management of breast cancer from multiparametric MRI

Nature Communications
Breast Magnetic Resonance Imaging (MRI) demonstrates the highest sensitivity for breast cancer detection among imaging modalities and is standard practice for high-risk women.
Luyang Luo, Mingxiang Wu, Mei Li, Yi Xin, Qiong Wang, Varut Vardhanabhuti, Winnie CW Chu, Zhenhui Li, Juan Zhou, Pranav Rajpurkar, Hao Chen   +10 more
doaj   +1 more source

De‐Escalation of Neoadjuvant Treatment for HER2‐Positive Breast Cancer

International Journal of Cancer, Volume 159, Issue 10, Page 2393-2402, 15 November 2026.
ABSTRACT With improved prognosis in early HER2‐positive breast cancer, safely de‐escalating treatment is increasingly investigated to minimize overtreatment. This article focuses on neoadjuvant de‐escalation strategies for HER2‐positive breast cancer.
Yiyin Ma, Dedian Chen, Sheng Huang
wiley   +1 more source

Preliminary investigation on predicting postoperative glioma recurrences based on a multiparametric radiomics model

Frontiers in Oncology
BackgroundThe early prediction of postoperative recurrence and high recurrence area of gliomas is important for individualized clinical treatment. This study aimed to evaluate the performance of a magnetic resonance imaging (MRI)-based multiparametric ...
Fang-Xiong Fu, Fang-Xiong Fu, Guo Li, Lan Hong, Wang-Sheng Chen   +4 more
doaj   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Combined ADC and T2 Mapping in the Prostate Using a 3D Reduced FOV Sequence

Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2292-2308, November 2026.
ABSTRACT Purpose To develop a 3D reduced FOV sequence for combined ADC and T2 mapping in the prostate in a single scan. Methods A 3D ADC and T2 mapping reduced FOV acquisition is enabled using T2 and diffusion preparation modules with slab‐selective tip‐down pulses and magnitude stabilizer gradients.
Yannik Ott, Sarah McElroy, Raphael Tomi‐Tricot, Carolyn Horst, Patricia A. Gutierrez, Rahul Khamar, Omar Darwish, Vicky Goh, Radhouene Neji   +8 more
wiley   +1 more source

Phase‐Sensitive Modeling Improves Fat DESPOT Multiparametric Relaxation Mapping in Fat‐Water Mixtures

Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2336-2349, November 2026.
ABSTRACT Purpose To improve on a multiparametric technique—known as Fat DESPOT—to map the fat‐ and water‐specific R1 (R1f, R1w), R2*, and proton density fat fraction (PDFF) by upgrading the parameter initialization and introducing explicit model sensitivity to the complex phase of the water and fat signals.
Renée‐Claude Bider, Cristian Ciobanu, Jorge Campos Pazmiño, Véronique Fortier, Evan McNabb, Ives R. Levesque   +5 more
wiley   +1 more source

Dosimetric evaluation of systematic source position uncertainty along the source path and robust planning during MRI‐only cervical HDR brachytherapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 10, October 2026.
Abstract Background The knowledge of the dosimetric impact of systematic source position uncertainty and the use of a methodology for robust treatment planning against such uncertainty can help improve the quality of treatment plans, during MR‐only cervical brachytherapy treatment.
Amritpal Singh, Raffi Karshafian, Ananth Ravi, Moti Raj Paudel   +3 more
wiley   +1 more source

Multiparametric Quantitative MRI of Peripheral Nerves to Differentiate Demyelinating From Axonal Polyneuropathies

Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 1077-1088, October 2026.
ABSTRACT Background Differentiating demyelinating from axonal polyneuropathies helps for accurate diagnosis and treatment. However, the current clinical tools lack sensitivity to confirm demyelination in peripheral nerves, particularly for proximal nerves.
Jesus E. Fajardo, Vivian B. Truong, Yang Xuan, Sara E. Benitez, Mary L. Vo, Bo Hu, Richard D. Dortch, Jun Li, Yongsheng Chen   +8 more
wiley   +1 more source