Results 181 to 190 of about 9,483,639 (271)

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

The pitfalls of multiple-choice questions in generative AI and medical education. [PDF]

Sci Rep
Singh S, Alyakin A, Alber DA, Stryker J, Tong APS, Sangwon K, Goff N, De La Paz M, Hernandez-Rovira M, Park KY, Leuthardt EC, Oermann EK.   +11 more
europepmc   +1 more source

A nationwide student survey on biochemistry learning resources in Italy

FEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti, Ivano Eberini, Maria Luisa Genova, Francesca Mensitieri, Francesco Malatesta   +4 more
wiley   +1 more source

Human-Edited Generative AI-Assisted Multiple-Choice Questions in Postgraduate Family Medicine: Blinded Cross-Sectional Comparative Psychometric Study. [PDF]

JMIR Med Educ
Sze KP, Lim JQ, Loke YM, Ding TYG, Wee WC, Chen T, Wu JL, Bansal V, Fong QW, Chow M.   +9 more
europepmc   +1 more source

Multiple Choice Questions in Dermatology [PDF]

Archives of Disease in Childhood, 1994
openaire   +2 more sources

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Psychometric performance and student perceptions of AI- versus student-generated multiple-choice questions: a single-center randomized controlled trial. [PDF]

BMC Med Educ
Al-Najafi D, Krause KD, Wang Y, Zuo QK, Koblanski ME, Leong CJ, Schmidt E, Faran M, Verma V, Vyas R, Campbell M, Hwang J, Deng J, Palepu A.   +13 more
europepmc   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Multiple choice questions on Rheumatology

Journal of Mahatma Gandhi Institute of Medical Sciences, 2014
doaj  

Performance Evaluation of Large Language Models in Multilingual Medical Multiple-Choice Questions: Mixed Methods Study. [PDF]

JMIR Med Educ
Strasser LM, Anschuetz W, Dennstädt F, Hastings J.   +3 more
europepmc   +1 more source