Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics
Advanced Science, EarlyView.The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu +4 more
wiley +1 more source
Developing a programme theory of implementing patient-reported outcome measures for older people living with severe frailty: a mixed methods study using the consolidated framework for implementation research. [PDF]
J Patient Rep OutcomesHoward FD +4 more
europepmc +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
Advanced Science, EarlyView.The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
An MADM approach for the assessment of eye lenses with fuzziness of using prioritized weighted operators. [PDF]
Sci RepHu C +8 more
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao +14 more
wiley +1 more source
Bio-Derived Metamaterials: A Hierarchical Biomimetics-Based Evaluation System for Cross-Scale Performance in Chaozhou Woodcarving. [PDF]
Biomimetics (Basel)Wu F, Li L, Xiao C.
europepmc +1 more source
Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks
Advanced Science, EarlyView.This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen +11 more
wiley +1 more source
A pilot feasibility study of human-centered design for cirrhosis care: Development and pilot testing of SMARTLiver prototype, a FHIR-based clinical decision support system for hepatology. [PDF]
PLOS Digit HealthSunchu K +3 more
europepmc +1 more source
The 10-year anniversary of the dissemination and implementation models in health interactive webtool: History, refinement, use, and guidance. [PDF]
J Clin Transl SciRabin BA +8 more
europepmc +1 more source
A study on intuitionistic fuzzy generating function using T-Norm, T-Conorm operators to enhance night-time images for autonomous driving system. [PDF]
Sci RepRagavendirane MS, Dhanasekar S.
europepmc +1 more source