Results 61 to 70 of about 87,816 (237)

A CRISPR-Cas12b–Based Platform for Ultrasensitive, Rapid, and Highly Specific Detection of Hepatitis B Virus Genotypes B and C in Clinical Application

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Hepatitis B virus (HBV) is one of the most dangerous and prevalent agents that causes acute and chronic liver diseases in humans. Genotyping plays an important role in determining clinical outcomes and response to antiviral treatment in HBV–infected ...
Xu Chen   +8 more
doaj   +1 more source

Signatures of galactic magnetic lensing upon ultra high energy cosmic rays [PDF]

open access: yes, 2000
We analyse several implications of lensing by the regular component of the galactic magnetic field upon the observed properties of ultra high energy cosmic rays.
Harari, Diego   +2 more
core   +2 more sources

Excitation of multiple 2-mode parametric resonances by a single driven mode

open access: yes, 2017
We demonstrate autoparametric excitation of two distinct sub-harmonic mechanical modes by the same driven mechanical mode corresponding to different drive frequencies within its resonance dispersion band. This experimental observation is used to motivate
Do, Cuong   +2 more
core   +1 more source

Population genetics of trypanosoma brucei rhodesiense: clonality and diversity within and between foci [PDF]

open access: yes, 2013
African trypanosomes are unusual among pathogenic protozoa in that they can undergo their complete morphological life cycle in the tsetse fly vector with mating as a non-obligatory part of this development.
A MacLeod   +70 more
core   +6 more sources

Analysis and elimination of hysteresis and noisy precursors in power amplifiers [PDF]

open access: yes, 2006
Power amplifiers (PAs) often exhibit instabilities leading to frequency division by two or oscillations at incommensurate frequencies. This undesired behavior can be detected through a large-signal stability analysis of the solution.
Jeon, Sanggeun   +2 more
core   +1 more source

Bridge expansion joint in road transition curve: effects assessment on heavy vehicles [PDF]

open access: yes, 2017
Properly-designed road surfaces provide a durable surface on which traffic can pass smoothly and safely. In fact, the main causes that determine the structural decay of the pavement and its parts are the traffic loads.
Bonin   +10 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Characterization in bi-parameter space of a non-ideal oscillator [PDF]

open access: yes, 2017
The authors thank scientific agencies CAPES, CNPq (112952/2015-1), and FAPESP (2011/ 19269-11). M. S.
Balthazar, J. M.   +4 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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