Results 51 to 60 of about 1,289,762 (297)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Discrimination and well-being amongst the homeless: The role of multiple group membership

Frontiers in Psychology, 2015
The homeless are a vulnerable population in many respects. Those experiencing homelessness not only experience personal and economic hardship they also frequently face discrimination and exclusion because of their housing status.
Melissa eJohnstone, Jolanda eJetten, Genevieve Anita Dingle, Cameron eParsell, Zoe C Walter   +4 more
doaj   +1 more source

Validation of Computer-Adaptive Contrast Sensitivity as a Tool to Assess Visual Impairment in Multiple Sclerosis Patients

Frontiers in Neuroscience, 2021
BackgroundImpairment of visual function is one of the major symptoms of people with multiple sclerosis (pwMS). A multitude of disease effects including inflammation and neurodegeneration lead to structural impairment in the visual system.
Sina C. Rosenkranz, Sina C. Rosenkranz, Barbara Kaulen, Barbara Kaulen, Hanna G. Zimmermann, Hanna G. Zimmermann, Ava K. Bittner, Ava K. Bittner, Michael Dorr, Jan-Patrick Stellmann, Jan-Patrick Stellmann, Jan-Patrick Stellmann, Jan-Patrick Stellmann   +12 more
doaj   +1 more source

Discriminating Minimal SUGRA and Minimal Gauge Mediation Models at the Early LHC

, 2012
Among various supersymmetric (SUSY) standard models, the gravity mediation model with a neutralino LSP and the gauge mediation model with a very light gravitino are attractive from the cosmological view point.
E Nakamura, Eita Nakamura, G Aad, G Aad, G Aad, G Aad, G Aad, G Corcella, G Marchesini, H Pagels, J Alwall, K Hamaguchi, K Hamaguchi, K Kawagoe, M Asano, M Fairbairn, M Viel, ML Mangano, N Arkani-Hamed, S Frixione, Satoshi Shirai, Shoji Asai, T Sjöstrand   +22 more
core   +1 more source

Hyperspectral discrimination of tree species with different classifications using single- and multiple-endmember. [PDF]

, 2013
Discrimination of tree species with different ages is performed in three classifications using hyperspectral data. The first classification is between Broadleaves and pines; the second classification is between Broadleaves, Corsican Pines, and Scots ...
Abdul Rashid M. Shariff, Azadeh Ghiyamat, Baoxin, Bruzzone, Castro-Esau, Chein, Cho, Clark, Danson, Dian, Dibley, Du, Du, Dudeni, Fairweather, Ghafour Amouzad Mahdiraji, Ghiyamat, Hansen, Hansen, He, Helmi Zulhaidi M. Shafri, Hillnhutter, Jie, Kruse, Kumar, Lee, Mundt, Portigal, Pu, Roberts, Robila, Shafri, Sharma, Shattri Mansor, Sobhan, Sánchez-Azofeifa, Vaiphasa, van der Meer, Vyas, Wang, Youngentob, Yuhas, Zarco-Tejada, Zhang   +43 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Item statistics derived from three-option versions of multiple-choice questions are usually as robust as four- or five-option versions: implications for exam design. [PDF]

, 2018
Different versions of multiple-choice exams were administered to an undergraduate class in human physiology as part of normal testing in the classroom. The goal was to evaluate whether the number of options (possible answers) per question influenced the ...
Loudon, Catherine, Macias-Muñoz, Aide
core  

Unambiguous discrimination among oracle operators

, 2007
We address the problem of unambiguous discrimination among oracle operators. The general theory of unambiguous discrimination among unitary operators is extended with this application in mind.
Chefles, Anthony, Kitagawa, Akira, Sasaki, Masahide, Takeoka, Masahiro, Twamley, Jason   +4 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Adaptive learning method for multiple-object detection in manufacturing

Advances in Mechanical Engineering, 2015
In manufacturing, vision-based inspections are effective nondestructive methods for implementing object discrimination. To minimize inspection times, multiple-object discrimination must be implemented for one inspection image.
Tsun-Kuo Lin
doaj   +1 more source