Results 61 to 70 of about 377,294 (261)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Barrier or stressor? The role of discrimination experiences in health service use
BMC Public Health, 2018 Background Discrimination is a well-established stressor that is substantially associated with poor health and a known contributor to health inequalities. However, the role of discrimination in health service use is less explored. This study will take an
Billy Gazard +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Gender inequalities at the intersection of discriminatory mecha-nisms
Sfera Politicii, 2012 The text aims to present less visible facet of discrimination by identifying social and cultural mechanisms that generate and maintain multiple forms of discrimination, the intersection of which gender has a central position, because he combine with all ...
Alina Hurubean
doaj
Discriminative Multiple Target Tracking [PDF]
, 2011 In this chapter, we introduce a metric learning framework to learn a single discriminative appearance model for robust visual tracking of multiple targets. The single appearance model effectively captures the discriminative visual information among the different visual targets as well as the background.
Xiaoyu Wang, Gang Hua, Tony X. Han
openaire +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Multi-Level Audio Classification Architecture
Advances in Electrical and Electronic Engineering, 2015 A multi-level classification architecture for solving binary discrimination problem is proposed in this paper. The main idea of proposed solution is derived from the fact that solving one binary discrimination problem multiple times can reduce the ...
Jozef Vavrek, Josef Juhar
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Intersectionality as a tool for clinical ethics consultation in mental healthcare
Philosophy, Ethics, and Humanities in MedicineBioethics increasingly recognizes the impact of discriminatory practices based on social categories such as race, gender, sexual orientation or ability on clinical practice.
Mirjam Faissner +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source