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Molecular cytogenetics of multiple drug resistance
Cytotechnology, 1993The refractory nature of many human cancers to multi-agent chemotherapy is termed multidrug resistance (MDR). In the past several decades, a major focus of clinical and basic research has been to characterize the genetic and biochemical mechanisms mediating this phenomenon.
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Multiple Drug Resistance Mechanisms in Cancer
Molecular Biotechnology, 2010Multiple drug resistance (multidrug resistance; MDR), a phenomenon whereby human tumours that acquire resistance to one type of therapy are found to be resistant to several other drugs that are often quite different in both structure and mode of action, has been recognised clinically for several decades. An important advance in our understanding of MDR
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Drug resistance in multiple myeloma.
Pathologie-biologie, 1999Multidrug resistance (MDR) is a pleiotropic resistance against several unrelated drugs. It may be induced by prolonged exposure of cells to drugs such as doxorubicin, etoposide and vinca alkaloids. Once MDR develops in clinical tumors, it is a major obstacle for the improvement of treatment of multiple myeloma (MM).
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[Multiple resistance to drugs by MRSA].
Nihon rinsho. Japanese journal of clinical medicine, 1992Most methicillin-resistant Staphylococcus aureus (MRSA) isolates are multiply resistant to various antimicrobial agents. Therefore, MRSA strains have become a serious problem in the clinical setting. However, it should be noted that the frequency of isolation of strains resistant to aminoglycoside and minocycline was not significantly different between
M, Inoue, N, Hasobe, Y, Hirata, T, Okubo
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Autophagy: A Potential Therapeutic Target to Tackle Drug Resistance in Multiple Myeloma
International Journal of Molecular Sciences, 2023Hamed Bashiri +2 more
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Emerging Therapeutic Strategies to Overcome Drug Resistance in Multiple Myeloma
Cancers, 2021Lorraine N Davis +2 more
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Multiple-Drug-Resistant Salmonella typhi
Clinical Infectious Diseases, 1993A S, Mourad +8 more
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Multiple Myeloma: Available Therapies and Causes of Drug Resistance
Cancers, 2020Rui Bergantim +2 more
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Conformational adjustment overcomes multiple drug-resistance mutants of tropomyosin receptor kinase
European Journal of Medicinal Chemistry, 2022Lin-Sheng Zhuo +2 more
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