Results 1 to 10 of about 65,584 (272)

Multiple endocrine neoplasia type 1 with neuroglycopenic symptoms with a novel heterozygous MEN1 gene mutation [PDF]

World Journal of Surgical Oncology
Background Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder caused by mutations in the MEN1 gene located on the long arm of chromosome 11. Case presentation.
Xinchen Jiang, Shixiong Tang, Guoqing Yang, Lite Ge, Fan Peng   +4 more
doaj   +2 more sources

Double mutation for multiple endocrine neoplasia associated with congenital adrenal hyperplasia [PDF]

Endocrinology, Diabetes & Metabolism Case Reports
A 39 year old female with signs of hyperandrogenism, was diagnosed with congenital adrenal hyperplasia after a cortrosyn test. Abdominal tomography showed a nodular image in the right adrenal gland, measuring 1.9 × 3.1 cm, 26 UH.
Watrusy Lima de Oliveira, Eloilda Maria de Aguiar Silva, Carlos Eduardo de Melo Oliveira, Wellington Alves Filho, Maria Cecília Martins Costa, Renata Carvalho de Alencar, Carla Antoniana de Almeida Vieira, Ana Rosa Pinto Quidute   +7 more
doaj   +2 more sources

Multiple endocrine neoplasia type 2 – solving the puzzle [PDF]

Journal of Family Medicine and Primary Care, 2023
Multiple endocrine neoplasia (MEN) are tumors that involve two or more endocrine glands. It can also involve other organs and tissues as well. Out of the four types of MEN type 2 is the most common.
Ajay K. Jha, Ashok Sunder, Sridhar Pradhan   +2 more
doaj   +2 more sources

Pituitary Neuroendocrine Tumors in Multiple Endocrine Neoplasia [PDF]

Endocrinology and Metabolism
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal-dominant disorder characterized by tumors of the pituitary, parathyroid, and endocrine-gastrointestinal tract. Pituitary neuroendocrine tumors (PitNETs) occur in about 40% of MEN1 cases, with 10%
Sang Ouk Chin, Constance Chik, Toru Tateno   +2 more
doaj   +2 more sources

Challenges in molecular diagnosis of multiple endocrine neoplasia [PDF]

Frontiers in Endocrinology
Multiple endocrine neoplasia (MEN) is a group of rare genetic diseases characterized by the occurrence of multiple tumors of the endocrine system in the same patient. The first MEN described was MEN1, followed by MEN2A, and MEN2B.
Pauline Romanet, Théo Charnay, Nicolas Sahakian, Thomas Cuny, Frédéric Castinetti, Anne Barlier   +5 more
doaj   +2 more sources

Prospective Genetic Screening in Multiple Endocrine Neoplasia Syndromes [PDF]

Children
Multiple endocrine neoplasia syndromes are a rare but potentially fatal pathology due to the lack of early diagnosis. We have performed a narrative review of the medical literature, summarizing the main clinical concepts useful in current clinical ...
Diana Paun, Dana Tilici, Sorin Paun, Alexandra Mirica   +3 more
doaj   +2 more sources

MULTIPLE ENDOCRINE NEOPLASIA TYPE 2B: A CASE REPORT

Alʹmanah Kliničeskoj Mediciny, 2016
This article provides our own clinical observation of the patient with multiple endocrine neoplasia type 2B (MEN2B) associated with a  germinal mutation in the RET proto-oncogene.
E. A. Troshina, N. V. Mazurina, O. V. Logvinova   +2 more
doaj   +3 more sources

Genotype-phenotype correlation in multiple endocrine neoplasia type 1 [PDF]

JCI Insight
BACKGROUND Among patients with multiple endocrine neoplasia type 1 (MEN1), 80% develop duodenopancreatic neuroendocrine tumors (dpNETs), of whom 15%–25% die of metastasis. There is a need to identify biomarkers to predict aggressive disease.
Charlita C. Worthy, Rana Tora, Chandra N. Uttarkar, James M. Welch, Lynn Bliss, Craig Cochran, Anisha Ninan, Sheila Kumar, Stephen Wank, Sungyoung Auh, Lee S. Weinstein, William F. Simonds, Sunita K. Agarwal, Jenny E. Blau, Smita Jha   +14 more
doaj   +2 more sources

Update on the clinical management of multiple endocrine neoplasia type 1

Clinical Endocrinology, 2022
This review provides an overview of novel insights in the clinical management of patients with Multiple Endocrine Neoplasia Type 1, focusing on the last decade since the last update of the MEN1 guidelines.
C. Pieterman, G. Valk
semanticscholar   +1 more source

Multiple endocrine neoplasia syndrome

Український радіологічний та онкологічний журнал, 2021
Background. Multiple endocrine neoplasia type 1 is a rare inherited disease that combines heterogeneous autosomal inherited disorders, the pathogenesis of which is based on hyperplasia or tumor transformation of several neuro- endocrine glands.
М. В. Красносельський, А. В. Свинаренко, Н. С. Підченко, А. С. Сімбірьова   +3 more
doaj   +1 more source