Results 21 to 30 of about 65,584 (272)

Clinical practice guidelines for multiple endocrine neoplasia type 1 (MEN1).

Journal of Clinical Endocrinology and Metabolism, 2012
OBJECTIVE The aim was to provide guidelines for evaluation, treatment, and genetic testing for multiple endocrine neoplasia type 1 (MEN1). PARTICIPANTS The group, which comprised 10 experts, including physicians, surgeons, and geneticists from ...
R. Thakker, P. Newey, G. Walls, J. Bilezikian, H. Dralle, P. Ebeling, S. Melmed, A. Sakurai, F. Tonelli, M. Brandi   +9 more
semanticscholar   +1 more source

Biochemical, bone and renal patterns in hyperparathyroidism associated with multiple endocrine neoplasia type 1

Clinics, 2012
Primary hyperparathyroidism associated with multiple endocrine neoplasia type I (hyperparathyroidism/multiple endocrine neoplasia type 1) differs in many aspects from sporadic hyperparathyroidism, which is the most frequently occurring form of ...
Delmar M. Lourenço Jr., Flavia L. Coutinho, Rodrigo A. Toledo, Tatiana Denck Gonçalves, Fabio L. M. Montenegro, Sergio P. A. Toledo   +5 more
doaj   +1 more source

Multiple endocrine neoplasia type 2

Definitions, 2020
Hereditary medullary thyroid carcinoma (MTC) presents within the context of 3 genetic syndromes. Multiple endocrine neoplasia type 2A (MEN2A, Sipple’s syndrome) is an autosomal-dominant genetic syndrome that includes MTC, pheochromocytoma, and primary ...
Melanie L. Richards
semanticscholar   +1 more source

Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1 [PDF]

DEN Open
ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Hirakawa N, Kitamura K, Yamamoto K, Tadokoro K, Akita Y, Uemura J, Yamanishi F, Abe M, Nakatsugawa M, Itoi T.   +9 more
europepmc   +2 more sources

Variable clinical expression in patients with a germline MEN1 disease gene mutation: clues to a genotype-phenotype correlation

Clinics, 2012
Multiple endocrine neoplasia type 1 is an inherited endocrine tumor syndrome, predominantly characterized by tumors of the parathyroid glands, gastroenteropancreatic tumors, pituitary adenomas, adrenal adenomas, and neuroendocrine tumors of the thymus ...
Cornelis J. Lips, Koen M. Dreijerink, Jo W. Höppener   +2 more
doaj   +1 more source

Multiple Endocrine Neoplasia or Accidental Association?

European Journal of Case Reports in Internal Medicine, 2020
Pheochromocytoma, papillary thyroid carcinoma and hyperparathyroidism have rarely been reported together. Whether this association is coincidental or results from an unknown genetic predisposition is difficult to ascertain.
Georgiana Cristina Taujan, Felicia Baleanu, Linda Spinato, Ruth Duttmann, Rafik Karmali, Laura Iconaru   +5 more
doaj   +1 more source

Multiple Endocrine Tumors Associated with Germline MAX Mutations: Multiple Endocrine Neoplasia Type 5?

Journal of Clinical Endocrinology and Metabolism, 2020
CONTEXT Pathogenic germline MAX variants are associated with pheochromocytoma and paraganglioma (PPGL), pituitary neuroendocrine tumors and, possibly, other endocrine and non-endocrine tumors. OBJECTIVE To report two families with germline MAX variants,
Amanda Seabrook, J. Harris, Sofia B Velosa, Edward J. Kim, A. McInerney-Leo, T. Dwight, Jason I Hockings, Nicholas G Hockings, J. Kirk, P. Leo, Amanda J Love, C. Luxford, M. Marshall, O. Mete, David Pennisi, M. Brown, A. Gill, G. I. Hockings, R. Clifton-Bligh, E. Duncan   +19 more
semanticscholar   +1 more source

Over-representation of the G12S polymorphism of the SDHD gene in patients with MEN2A syndrome

Clinics, 2012
OBJECTIVE: To evaluate whether germline variants of the succinate dehydrogenase genes might be phenotypic modifiers in patients with multiple endocrine neoplasia type 2.
Nikoletta Lendvai, Miklos Tóth, Zsuzsanna Valkusz, Gabriella Bekő, Nikolette Szücs, Éva Csajbók, Péter Igaz, Balázs Kriszt, Balázs Kovács, Károly Rácz, Attila Patócs   +10 more
doaj   +1 more source

Thymic atypical carcinoid tumors with elevated mitotic counts in a patient with multiple endocrine neoplasia: A case report

Thoracic Cancer, 2023
Thymic neuroendocrine tumors associated with multiple endocrine neoplasia are only defined as carcinoid and are not associated with large‐cell neuroendocrine carcinoma (LCNEC).
Shuntaro Hiro, Shuhei Teranishi, Tomoe Sawazumi, Satoshi Nagaoka, Chihiro Sugimoto, Hirokazu Nagayama, Wataru Segawa, Yukihito Kajita, Chihiro Maeda, Sousuke Kubo, Kenichi Seki, Ken Tashiro, Nobuaki Kobayashi, Masaki Yamamoto, Makoto Kudo, Takeshi Kaneko   +15 more
doaj   +1 more source

Surgery for multiple endocrine neoplasia type 1‐related insulinoma: long‐term outcomes in a large international cohort

British Journal of Surgery, 2020
Insulinomas are found in 10–15 per cent of patients with multiple endocrine neoplasia type 1 (MEN1) and lead to life‐threatening hypoglycaemia. Surgical outcome and the optimal surgical strategy for MEN1‐related insulinoma are unknown.
D. van Beek, S. Nell, H. Verkooijen, I. B. Borel Rinkes, G. Valk, M. Vriens, P. A. D. D. K. J. N. D. I. M. L. R. E. L. E. P. L. J. Goudet Vella Donegan Bartsch Manoharan Perrier Chr, P. Goudet, A. Vella, D. Donegan, D. K. Bartsch, J. Manoharan, N. D. Perrier, I. Christakis, M. L. Brandi, R. Zarnegar, E. L. Postma, E. Kebebew, P. Nockel, L. Brunaud, J. D. Pasternak, W. Kluijfhout, C. Sturgeon, S. Giri, B. Bonsing, C. H. van Eijck, H. van Goor, R. H. J. de Kleine, E. J. N. van Dijkum, C. C. Dejong   +29 more
semanticscholar   +1 more source