Results 101 to 110 of about 681,106 (299)
Improved impact-resistant boron-aluminum composites for use as turbine engine fan blades [PDF]
Efforts to improve the impact resistance of B/Al are reviewed and analyzed. Thin sheet Charpy and Izod impact tests and standard full size Charpy impact tests were conducted on unidirectional and angleply composites containing 4, 5.6 and 8 mil boron in ...
Mcdanels, D. L., Signorelli, R. A.
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Multiple Boundary Layer Instability Modes with Nonequilibrium and Wall Temperature Effects Using LASTRAC [PDF]
Prediction and control of boundary layer transition from laminar to turbulent is important to many flow regimes and vehicle designs, including vehicles operating at hypersonic conditions where nonequilibrium effects may be encountered.
Chang, C.-L., Kline, H. L., Li, F.
core +1 more source
Studies of in-service and laboratory failures of metal-oxide distribution surge arresters [PDF]
, 2003 We describe the findings from tests and inspections of arresters withdrawn from service, the results of laboratory studies with multipulse lightning currents and high temporary over-voltages, and comparisons of in-service and laboratory failure modes. We
Darveniza, M., Saha, T. K., Wright, S.
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Multiple Failure Modes，Causes and Prevention of Random Fracture for Hard Tooth Flank Gears
Jixie chuandong, 2022 The history and evolution of the random fracture terms，the morphological features，failure examples，causes and preventive measures of various random fracture modes are comprehensively discussed.
Xiaolu Zhu
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Effect of fiber diameter and matrix alloys on impact-resistant boron/aluminum composites [PDF]
Efforts to improve the impact resistance of B/Al are reviewed and analyzed. Nonstandard thin-sheet charpy and Izod impact tests and standard full-size Charpy impact tests were conducted on composites containing unidirectional 0.10mm, 0.14mm, and 0.20mm ...
Mcdanels, D. L., Signorelli, R. A.
core +1 more source
The Virtues of Redundancy in Legal Thought [PDF]
, 1990 Redundancy has a bad reputation among legal intellectuals. When someone says, for example, that the ninth and tenth amendments are redundant, we can be pretty sure that this person attaches little importance to these constitutional provisions.
Barnett, Randy E
core +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Enhanced Monte Carlo-assisted Safety Monitoring in Process Industries: a Tank System Case Study
Chemical Engineering TransactionsSafety is a critical concept in process industries. However, the complexity as the characteristic of process industries brings different challenges when conducting industrial monitoring for the sake of system safety, which is summarized as lacking a ...
Huxiao Shi +4 more
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