Results 71 to 80 of about 676,606 (300)

Reliability analysis of corrosion affected underground steel pipes considering multiple failure modes and their stochastic correlations

open access: yesTunnelling and Underground Space Technology, 2019
This paper presents a methodology for determining the probability of system failure of corrosion affected steel pipelines with multiple failure modes. The failure modes include fracture, strength failure, deflection and buckling and they are all modelled
G. Fu   +3 more
semanticscholar   +1 more source

An efficient hybrid reliability analysis method with application to the harmonic drive.

open access: yesPLoS ONE
The harmonic drive is a new type of high-efficiency gear transmission system, widely used in precision machinery, robotics, and aerospace due to its compact structure and high transmission accuracy, and the multiple uncertain parameters in it will ...
Jingqi Cui   +3 more
doaj   +1 more source

Semiparametric Estimates and Goodness-of-Fit Tests for Tire Wear and Failure Time Data

open access: yesNonlinear Analysis, 2002
The goodness-of-fit test for tire wear and failure time data with multiple failure modes is proposed. Parametric estimators of traumatic event cumulative intensities and semiparametric estimates of various reliability characteristics are given and their ...
Rūta Levulienė
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Step-path failure mechanism of rock slopes based on crack coalescence modes in rock mass

open access: yesYantu gongcheng xuebao, 2017
The crack propagation and coalescence mode play an important role in the step-path failure mechanism of rock slopes. By using the discrete element method (DEM), the coalescence modes between two pre-existing cracks with different geometries (rock bridge ...
ZHU Lei , HUANG Run-qiu , YAN Ming , CHEN Guo-qing
doaj   +1 more source

Safety Analysis of Storm Sewer Using Probability of Failure and Multiple Failure Mode

open access: yesJournal of Korea Water Resources Association, 2010
AFDA (Approximate Full Distribution Approach) model of FORM (First-Order Reliability Model) which can quantitatively calculate the probability that storm sewer reach to performance limit state was developed in this study. It was defined as a failure if amount of inflow exceed the capacity of storm sewer.
Hyuk-Jae Kwon, Cheol-Eung Lee
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reliability Analysis of High-Pressure Tunnel System Under Multiple Failure Modes Based on Improved Sparrow Search Algorithm–Kriging–Monte Carlo Simulation Method

open access: yesApplied Sciences
It is often difficult for a structural safety design method based on deterministic analysis to fully and reasonably reflect the randomness of mechanical parameters, while the traditional reliability analysis method has a large calculation cost and low ...
Yingdong Wang, Chen Xing, Leihua Yao
doaj   +1 more source

Active learning surrogate models for the conception of systems with multiple failure modes [PDF]

open access: yesReliability Engineering & System Safety, 2016
The conception (or risk assessment) of complex mechanical systems has to take into account a series of constraints. Such constraints can be due to certification criteria, performance objectives, cost limitations, and so on. In this context, the role of simulation has kept increasing for the last decades, as it should be able to predict if a given ...
openaire   +3 more sources

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