Results 151 to 160 of about 6,578,993 (340)

Combining antigen-specific T cells with T-cell engager therapy induces a molecular signature that favors T-cell fitness

Blood Immunology & Cellular Therapy
: Both adoptive cellular therapy with tumor antigen–specific T cells and redirection of endogenous T cells with bispecific tumor-specific T-cell engaging antibodies rely on CD8+ T cell effector function. The two approaches use complementary mechanisms of
Manpreet Bariana, Sidharth Anand, Mark Batistick, Elena Cassella, Shaina A. Anuncio, Ariel Aptekmann, David S. Siegel, Mathias Oelke, Sojung Kim, Ruipeng Wang, Jack A. Ragheb, Johannes L. Zakrzewski   +11 more
doaj   +1 more source

Immunophenotypic characteristics of plasma cells in POEMS syndrome

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract To analyze the immunophenotypic characteristics of plasma cells in patients with polyneuropathy, organomegaly, endocrinopathy, myeloma protein, and skin changes (POEMS) syndrome. This retrospective study included patients with POEMS syndrome hospitalized in the Department of Hematology, Huashan Hospital, from September 2017 to August 2025 ...
Zhenhua Wang, Tianling Ding, Beiqian Wu, Qiang Niu, Leyao Gu, Yan Yuan, Ping Zhu   +6 more
wiley   +1 more source

International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma.

The Lancet Oncology, 2014
S. Rajkumar, M. Dimopoulos, A. Palumbo, J. Bladé, G. Merlini, M. Mateos, Shaji K. Kumar, J. Hillengass, E. Kastritis, P. Richardson, O. Landgren, B. Paiva, A. Dispenzieri, B. Weiss, X. Leleu, S. Zweegman, S. Lonial, L. Rosiñol, E. Zamagni, S. Jagannath, O. Sezer, S. Kristinsson, J. Caers, S. Usmani, J. Lahuerta, H. Johnsen, M. Beksaç, M. Cavo, H. Goldschmidt, E. Terpos, R. Kyle, K. Anderson, B. Durie, J. Miguel   +33 more
semanticscholar   +1 more source

Prevalence of transthyretin cardiac amyloidosis in undifferentiated heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1176-1182, April 2025.
Abstract Aims Transthyretin amyloid cardiomyopathy (ATTR‐CM) is an increasinglyrecognized cause of heart failure with preserved ejection fraction (HFpEF), which may be diagnosed non‐invasively using 99mTc 3,3‐diphosphono‐1,2‐propanodicarboxylic acid (DPD) scintigraphy‐based diagnostic criteria.
L. Healy, G. Giblin, A. Gray, N. Starr, L. Murphy, D. O'Sullivan, E. Kavanagh, C. Howley, C. Tracey, E. Morrin, A. McDaid, A. Clarke, J.O. O'Neill, E. Joyce, M. O'Connell, N. G. Mahon   +15 more
wiley   +1 more source

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

International Journal of Cancer, EarlyView.
What's New? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado, Angelica Macauda, Antonio José Cabrera‐Serrano, Hauke Thomsen, Murat Güler, Rob Ter Horst, Bethany van Guelpen, Pavel Vodicka, Stefano Landi, Subhayan Chattopadhyay, Pelin Ünal, Lucía Ruiz‐Durán, Delphine Casabonne, Hartmut Goldschmidt, Istemi Serin, María Carretero‐Fernández, Elena Cabezudo, Fernando Reyes‐Zurita, Aaron D. Norman, Ramón García‐Sanz, Gabriele Capurso, Per Hoffmann, Ulrika Pettersson‐Kymmer, Francisco Jiménez‐Romera, S. Vincent Rajkumar, Niels Weinhold, Ludmila Vodickova, Christian Langer, Angelika Stein, Abdulkadir Karismaz, Victor Moreno, Markus M. Nöthen, Karl‐Heinz Jöckel, Francesca Tavano, Joaquín Martínez‐López, Shaji K. Kumar, Juan Francisco Gutiérrez‐Bautista, Daniela Basso, Florentin Späth, Yolanda Benavente, Michelle A. T. Hildebrandt, Börge Schmidt, Tereza Sevcikova, Rui Manuel Vieira Reis, Yang Li, Miguel Ángel López‐Nevot, Mihai G. Netea, Daniele Campa, Alyssa Clay‐Gilmour, Susan L Slager, Kari Hemminki, Celine M Vachon, Asta Försti, Federico Canzian, Juan Sainz   +54 more
wiley   +1 more source

Author Correction: The biological significance of histone modifiers in multiple myeloma: clinical applications

Blood Cancer Journal, 2021
Hiroto Ohguchi, Teru Hideshima, Kenneth C. Anderson   +2 more
doaj   +1 more source

Sensitive Period Analysis of Adulthood BMI and Cancer Risk: An Individual Participant Data Meta‐Analysis of Over 720,000 Participants in the ABACus 2 Consortium

International Journal of Cancer, EarlyView.
Over a dozen cancers have been associated with excess body mass index, primarily in mid‐to‐late adulthood. Whether obesity‐related cancer risk differs across adulthood remains unclear. Using the Sensitive Periods Model and super‐landmarking approaches, this study found that higher BMI increased obesity‐related cancer risk across ages 30–65.
Nadin K. Hawwash, Matthew Sperrin, Glen P. Martin, Rashmi Sinha, Charles E. Matthews, Matthias B. Schulze, Anouk Hiensch, Pilar Amiano, Marian L. Neuhouser, Corinne E. Joshu, Elizabeth A. Platz, Heinz Freisling, Marc J. Gunter, Andrew G. Renehan   +13 more
wiley   +1 more source

Systemic and Local Adiposity in the Bone Marrow Microenvironment Associated With Improved Prognosis in Hodgkin Lymphoma: Imaging and Molecular Analysis

International Journal of Cancer, EarlyView.
Schematic overview of systemic and bone marrow‐specific adiposity in Hodgkin Lymphoma (HL). Body Mass Index was associated with bone marrow (BM) involvement, relapse, and mortality (1). In contrast, increased yellow marrow density was associated with poorer prognosis (2).
Andreia Matos, William P. Cawthorn, Joana Marinho‐Dias, Sofia Ramalheira, Susana Roncon, Dulcineia Pereira, Teresa Ribeiro, Carla Rodrigues, Mário Mariz, Ana Miranda, Helena Brízido, Manuel Bicho, Pedro Medeiros, Ana Carneiro, Fernanda Trigo, Pingzhao Hu, Flávia Pereira, Hugo Duarte, Calum D. Gray, Tom Macgillivray, Alan G. Ramsay, Maria J. Oliveira, Ricardo Ribeiro   +22 more
wiley   +1 more source

Role of minimal residual disease assessment in multiple myeloma

Haematologica
Multiple myeloma (MM) is a hematologic malignancy characterized by clonal proliferation of plasma cells. MM is a heterogeneous disease, featured by various molecular subtypes with different outcomes. With the advent of very efficient therapies including
Raphael Szalat, Kenneth Anderson, Nikhil Munshi   +2 more
doaj   +1 more source

Multiple myeloma [PDF]

Clinical Medicine, 2001
D, Samson, C, Singer
openaire   +2 more sources