Results 161 to 170 of about 51,890 (248)

Tranexamic Acid in Lower Extremity Endoprosthetic Reconstruction for Oncologic Indications: A Retrospective Comparative Study of 617 Patients

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives While tranexamic acid (TXA) reduces blood loss in orthopedic surgery, thromboembolic concerns in cancer patients have limited adoption in orthopedic oncology. This study evaluated TXA efficacy and safety in patients undergoing endoprosthetic reconstruction for oncologic indications.
Stephen W. Chenard, Akhil Rekulapelli, Riley S. Gilbertson, Connor S. Charton, William F. Hefley, Michael J. Colello, Jennifer L. Halpern, Herbert S. Schwartz, Daniel J. Johnson, Jonathan G. Schoenecker, Joshua M. Lawrenz   +10 more
wiley   +1 more source

Emerging combination therapies for the management of multiple myeloma: the role of elotuzumab

, 2017
Wei-Chih Chen,1 Abraham S Kanate,2,3 Michael Craig,2,3 William P Petros,1,3 Lori A Hazlehurst1–3 1Department of Pharmaceutical Sciences, School of Pharmacy, 2Osborn Hematopoietic Malignancy and Transplantation Program, West Virginia University ...
Chen WC, Petros WP, Kanate AS, Hazlehurst LA, Craig M   +4 more
core  

Elective Surgical Care Pathways Are Associated With Lower Fracture Rates at Presentation and Contribute to Superior Clinical Outcomes in Metastatic Bone Disease

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Metastatic bone disease (MBD) often necessitates orthopaedic surgical intervention, which occurs through either emergent or elective care pathways. This study compared post‐operative outcomes between patients undergoing elective versus emergent surgery for MBD involving the pelvis and appendicular skeleton. Methods We
Annalise G Abbott, Joseph K. Kendal, Benjamin Wajda, Golpira Elmi Assadzadeh, Shannon K. T. Puloski, Michael J. Monument   +5 more
wiley   +1 more source

MULTIPLE MYELOMA

Annals of Surgery, 1931
openaire   +3 more sources

Deresuscitation Informed by Ultrasound in Patients with Septic Shock Trial

Journal of Ultrasound in Medicine, EarlyView.
Objectives The venous excess ultrasound (VExUS) can be used at the point‐of‐care to identify venous overload and end‐organ congestion in an effort to individually tailor resuscitation and deresuscitation in patients with septic shock. Methods We conducted a pilot randomized controlled feasibility trial of VExUS‐guided fluid management in adult patients
Brendan Innes, Christopher Allison, Nicholas Seidler, Burton Shen, Andrew Fried, Gary Phillips, Andrew Levinson, Adeel Abbasi   +7 more
wiley   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

High-dose chemotherapy with hematopoietic stem cell transplantation for patients with advanced multiple myeloma [PDF]

, 2000
Straka, C., Emmerich, B., Bamberg, M., Budach, W., Einsele, H.   +4 more
core   +1 more source

Selective purging of human multiple myeloma cells from peripheral blood mononuclear cells: a preliminary study

, 2019
A-Jin Lee, Sang-Gyung Kim Department of Laboratory Medicine, Daegu Catholic University School of Medicine, Daegu, Korea Background: High-dose chemotherapy followed by autologous peripheral blood stem-cell transplantation are standards of therapy for ...
Lee AJ, Kim SG
core  

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu, Jin‐Hao Chen, Yan‐Fang Wang, Xiao Wu, Hui‐Yun Ni, Qiu‐Rong Zhang   +5 more
wiley   +1 more source

Multiple myeloma

HemaSphere, 2019
openaire   +4 more sources