Results 161 to 170 of about 6,578,993 (340)

Prognostic Value of Perioperative Anemia in Neurosurgical‐Oncological Treatment of Spinal Metastases

International Journal of Cancer, EarlyView.
High perioperative morbidity in patients undergoing surgery for spinal metastases highlights the need to identify modifiable risk factors, particularly the underexplored role of anemia. This study assessed associations between perioperative hemoglobin levels and complications, recurrence, and mortality in patients treated surgically for spinal ...
Marija Janjic, Logman Khalafov, Juliane Dittmer, Saif‐Eldin Abedellatif, Tim Lampmann, Harun Asoglu, Mohammed Jaber, Haitham Alenezi, Muriel Heimann, Matthias Schneider, Motaz Hamed, Marcus Thudium, Hartmut Vatter, Mohammed Banat   +13 more
wiley   +1 more source

t(11;14) multiple myeloma patient: minimal residual disease after 10 years of follow-up - a case report

Haematologica
Not available.
Sarah Decheiver, Anais Schavgoulidze, Sabrina Maheo, Pierre-Adrien Vion, Olivier Lucidarme, Jill Corre, Laurent Garderet   +6 more
doaj   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Dissecting immunophenotypic diversity in multiple myeloma via mass cytometry: a call for harmonized gating strategies

Frontiers in Immunology
Plasma cell disorders present challenges in phenotypic determination, as they range from monoclonality of plasma cells to multiple myeloma and plasma cell leukemia.
Mahmoud Singer, Milad Moloudizargari, Milad Moloudizargari, James Sanchez, Flavia Pichiorri, Flavia Pichiorri   +5 more
doaj   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

I-OPen: inferior outcomes of penta-refractory compared to penta-exposed multiple myeloma patients

Blood Cancer Journal, 2022
Sarvarinder K. Gill, Rashmi Unawane, Shuqi Wang, Jaeil Ahn, Adolfo Aleman, David S. Siegel, David H. Vesole, Harsh Parmar, Pooja Phull, Noa Biran   +9 more
doaj   +1 more source

Effect of Intravenous Immunoglobulin (IVIG) Supplementation on infection-free survival in recipients of BCMA-directed bispecific antibody therapy for multiple myeloma

Blood Cancer Journal
The main objective of this multi-institutional study is to understand the effect of primary intravenous immunoglobulin (IVIG) replacement on clinical outcomes in recipients of BCMA-directed bispecific antibody (bsAb), where infection remains an important
Meera Mohan, Aniko Szabo, Heloise Cheruvalath, Anna Clennon, Vineel Bhatlapenumarthi, Anannya Patwari, Metodi Balev, Divaya Bhutani, Asis Shrestha, Sharmilan Thanendrarajan, Binod Dhakal, Maurizio Zangari, Anup Trikannad, Sruthi Vellanki, Samer Al-Hadidi, Suzanne Lentzsch, Frits van Rhee, Aishee Bag, Anita D’Souza, Nishi Shah, Rajshekhar Chakraborty, Mansi R. Shah, Carolina Schinke   +22 more
doaj   +1 more source

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, EarlyView.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

Evaluating Value-Based Frameworks Used for Relapsed or Refractory Multiple Myeloma Regimens: ICER Report, ASCO Value Framework, and NCCN Evidence Blocks [PDF]

, 2017
BACKGROUND: With the continuous rise in costs for oncology drugs, the Institute for Clinical and Economic Review (ICER), the American Society of Clinical Oncology (ASCO) and the National Comprehensive Cancer Network (NCCN) have developed value-based ...
Chun, PharmD, Grace, Djatche, PharmD, Laurence M., Goble, PharmD, Joseph, Varga, PharmD, Stefan   +3 more
core   +1 more source

Evaluation of FilmArray Multiplex PCR Test Results in Bloodstream Infections in Oncological Patients

Journal of Clinical Laboratory Analysis, EarlyView.
In this study conducted at an oncology hospital, BCID2 panel results for the rapid identification of microorganisms and resistance genes in positive blood culture samples were compared with conventional culture methods. The BCID2 panel provided faster results and showed a high correlation with traditional methods.
İpek Mumcuoğlu, Sevgi Şahin, Esra Tavukcu, Neşe İnan, Ayşe Semra Güreser, Serap Süzük Yıldız, Tuba Dal   +6 more
wiley   +1 more source