RPL29 as a radiotherapy-sensitive prognostic biomarker in multiple myeloma. [PDF]
Wang Y, Jia Q, Liu H, Li Z, Ma Y.
europepmc +1 more source
Inhibition of E-Selectin (GMI-1271) or E-selectin together with CXCR4 (GMI-1359) re-sensitizes multiple myeloma to therapy [PDF]
Azab, Abdel Kareem +9 more
core +1 more source
Targeting Ikaros and Aiolos: Next‐Generation Cereblon E3 Ligase Modulators in MM
The graphical abstract illustrates the mechanism of action of cereblon E3 ligase modulators (CELMoDs) in multiple myeloma, highlighting cereblon‐mediated degradation of IKZF1 and IKZF3. Compared with classical immunomodulatory drugs (IMiDs), CELMoDs induce deeper IKZF1/3 depletion, leading to more pronounced suppression of the IRF4–MYC survival axis ...
Maria Eugenia Alvaro +12 more
wiley +1 more source
T Cells Dysfunction in Multiple Myeloma. [PDF]
Cai L +7 more
europepmc +1 more source
The technical and practical implementation of fundus photography in equids
Summary Background Fundus photography is an important diagnostic tool in human and veterinary medicine. Advances in research are increasing its accessibility in human medicine. However, there is a lack of studies on modern fundus photography in animals, particularly in horses. Objectives To assess the use of a portable fundus camera developed for human
I. Vierling, B. Wollanke, V. Franzen
wiley +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Characterization of cytogenetic abnormalities in Lebanese multiple myeloma patients. [PDF]
Najem G +12 more
europepmc +1 more source
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Treatment Initiation Among Black and White Older Adults With Multiple Myeloma: A SEER-Medicare Analysis. [PDF]
LeBlanc MR +12 more
europepmc +1 more source

