Results 271 to 280 of about 351,954 (346)

Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies

, 2018
Meng Lei, Huayun Feng, Enhe Bai, Hui Zhou, Jia Wang, Jingmiao Shi, Xueyuan Wang, Shihe Hu, Zhaogang Liu, Yongqiang Zhu   +9 more
openalex   +1 more source

Enhanced Detection of Multiple Myeloma Cells by Next‐Generation Flow Cytometry Following Density Gradient Medium Separation

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Following treatment, relapse of Multiple Myeloma (MM) occurs due to measurable residual disease (MRD). As therapeutic options expand, advances in response assessment become more critical, necessitating more sensitive MRD detection methods.
Aisling O'Brien, Vitaliy Mykytiv, Fiona O'Halloran   +2 more
wiley   +1 more source

Prognostic and therapeutic implications of disulfidptosis-related genes in multiple myeloma. [PDF]

Front Immunol
Zang Y, Zhou P, Dong H, Wang J, Cao R, Yang G, Wu Q, Sun Y, Sun Y.   +8 more
europepmc   +1 more source

Imaging flow cytometric detection of del(17p) in bone marrow and circulating plasma cells in multiple myeloma [PDF]

Thomas I. Mincherton, Stephanie Lam, Sarah E. Clarke, Henry Hui, Jacques A. J. Malherbe, Hun Sheng Chuah, M Hasib Sidiqi, Kathryn A. Fuller, Wendy N. Erber   +8 more
openalex   +1 more source

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

European Journal of Haematology, EarlyView.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot, Frederic Baleydier, Laure Pittet, Geraldine Blanchard‐Rohner   +3 more
wiley   +1 more source

Muscle Fat Infiltration in Patients with Multiple Myeloma: A Case-Control Study. [PDF]

Int J Gen Med
Zhu T, Zhou H, Zhang D, Chen X, Lu X.
europepmc   +1 more source

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

The FEBS Journal, EarlyView.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro, Martina Bergant Marušič, Justyna Broniarczyk   +2 more
wiley   +1 more source

Multiple myeloma in a man with breast cancer: A case report and literature review. [PDF]

Medicine (Baltimore)
Zhou X, Li MR, Sui XH, Shan NN.
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Utilization of real-world evidence in regulatory approvals for multiple myeloma therapies. [PDF]

Blood Cancer J
Taylor L, Chen A, Pierre A.
europepmc   +1 more source