Results 71 to 80 of about 91,752 (312)

Analysis and Comparisons of some Solution Concepts for Stochastic Programming Problems [PDF]

open access: yes
The aim of this study is to analyse the resolution of Stochastic Programming Problems in which the objective function depends on parameters which are continuous random variables with a known distribution probability.
María del Mar Muñoz   +3 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Multiple Objective Linear Programming in Supporting Forest Management

open access: yes, 1999
. This paper gives a brief introduction into multiple objective linear programming and discusses its possibilities in the area of forest management. We overview basic concepts, formulations, and principles of solving multiple objective linear programming
Pekka Korhonen
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Multi-objective optimization techniques in electricity generation planning

open access: yes, 2011
The objective of this research is to develop a framework of multi-objective optimization (MOO) models that are better capable of providing decision support on future long-term electricity generation planning (EGP), in the context of insufficient ...
Tuyiragize, Richard, Richard Tuyiragize
core  

Fractional Goal Programming for Fuzzy Solid Transportation Problem with Interval Cost

open access: yesFuzzy Information and Engineering, 2014
In this paper, we study a solid transportation problem with interval cost using fractional goal programming approach (FGP). In real life applications of the FGP problem with multiple objectives, it is difficult for the decision-maker(s) to determine the ...
B. Radhakrishnan, P. Anukokila
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

"Maximizing Conservation and In-Kind Cost Share: Applying Goal Programming to Forest Protection" [PDF]

open access: yes
This research evaluates the potential gains in benefits from using Goal Programming to preserve forestland. Two- and three-dimensional Goal Programming models are developed and applied to data from applicants to the U.S.
Jacob R. Fooks, Kent D. Messer
core  

FINANCIAL STRUCTURE OPTIMIZATION BY USING A GOAL PROGRAMMING APPROACH

open access: yesCroatian Operational Research Review, 2012
This paper proposes a new methodology for solving the multiple objective fractional linear programming problems using Taylor’s formula and goal programming techniques.
Tunjo Perić, Zoran Babić
doaj  

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