Results 61 to 70 of about 354,631 (302)

A case of gas gangrene with fatal outcome (gas gangrene: A case report) [PDF]

Serbian Journal of Anesthesia and Intensive Therapy
Introduction: The clinical course of gas gangrene is often rapidly progressive, with a fatal outcome in up to 80% of treated cases. The disease is most commonly a consequence of trauma or surgical interventions.
Pavić Slađana, Slović Radomir, Novković Aleksa, Pavić Aleksandra   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Successful Treatment of Multiple Organ Failure After Wasp Stings in an Elderly Patient

International Journal of Gerontology, 2012
Although all kinds of complication have been reported after wasp stings, multiple organ failure following wasp attacks is very rare. In the past, the mortality of patients with multiple organ failure treated by conventional therapy after wasp stings was ...
Wang Han-Min, Li Feng, Zhou Mei-Lan, Li Rong, Liu Hong-Bao, Huang Chen, Zhang Peng   +6 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Modern principles of treatment of the serious multisystem injuries

Бюллетень сибирской медицины, 2009
The analytical survey is concerned with the organizational aspects of the integrated study and thorough investigation of the problem of treatment of serious mechanical injuries.
A. V. Shteinle
doaj   +1 more source

Seawater-Associated Highly Pathogenic Francisella hispaniensis Infections Causing Multiple Organ Failure

Emerging Infectious Diseases, 2020
A rare case of Francisella hispaniensis infection associated with seawater exposure occurred in a deep-sea diving fisherman in Zhejiang, China. He had skin and soft tissue infection that progressed to bacteremia and multiple organ failure.
Hua Zhou, Qing Yang, Lisha Shen, Yake Yao, Jun Xu, Junhui Ye, Xiaomai Wu, Yunsong Yu, Ziqin Li, Jianying Zhou, Shangxin Yang   +10 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Multiple organ failure as onset of Mediterranean spotted fever: a review based on a case

Italian Journal of Medicine, 2016
Mediterranean spotted fever (MSF) is an infectious disease endemic in the southern regions of Italy, with an incidence of about 400 cases/year. The bacteria responsible of the disease is Rickettsia conorii, transmitted to humans by Rhipicephalus ...
Pasquale Mansueto, Aurelio Seidita, Accursia Bongiovì, Tiziana Catalano, Giuseppe Pirrone, Claudia Cusimano, Alberto D'Alcamo, Antonio Carroccio   +7 more
doaj   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Organ crosstalk and dysfunction in sepsis

Annals of Intensive Care
Sepsis is a dysregulated immune response to an infection that leads to organ dysfunction. Sepsis-associated organ dysfunction involves multiple inflammatory mechanisms and complex metabolic reprogramming of cellular function.
André Borges, Luís Bento
doaj   +1 more source