Results 51 to 60 of about 9,608,554 (246)

Skin Cancers Among Albinos at a University Teaching Hospital in Northwestern Tanzania: A Retrospective Review of 64 Cases. [PDF]

, 2012
Skin cancers are a major risk associated with albinism and are thought to be a major cause of death in African albinos. The challenges associated with the care of these patients are numerous and need to be addressed.
Rambau, Peter, Kamugisha, Erasmus, Nestory Masalu, Peter Rambau, Gilyoma, Japhet M, Phillipo L Chalya, Joseph B Mabula, Jaka, H., Giiti, G, Ssentongo Robert, Mchembe, Mabula D, Geofrey Giiti, Jaka, Hyasinta, Mabula D Mchembe, Masalu, N., Giiti, Geofrey, Robert, Ssentongo, Rambau, P., Erasmus Kamugisha, Robert, S., Chalya, Phillipo L, Masalu, Nestory, Gilyoma, J.M, Hyasinta Jaka, Mabula, J.B, Chalya, P.L, Japhet M Gilyoma, Kamugisha, E., Mabula, Joseph B, Mchembe, M.D   +29 more
core   +2 more sources

Simultaneous bilateral video-assisted thoracic surgery is safe and feasible for multiple primary lung cancers

Journal of Cardiothoracic Surgery
Background The treatment for bilateral synchronous multiple primary lung cancers (MPLC) remains challenging. Simultaneous bilateral video-assisted thoracic surgery (VATS) may be an optimal treatment with curative intent, but its safety and feasibility ...
Libing Yang, Chao Guo, Ye Zhang, Huizhen Jiang, Lian Ma, Hongsheng Liu, Shanqing Li   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Interpretation of the Multidisciplinary Expert Consensus on Diagnosi and Treatment of Multiple Lung Cancers by the Chinese Anti-Cancer Association

Xiehe Yixue Zazhi
With the widespread application of low-dose computed tomography (CT), the detection rate of multiple lung cancers (MLCs) is gradually increasing. The diagnosis and treatment of MLCs have become a major challenge in clinical practice in thoracic surgery ...
MAO Jianqi, YUAN Xiaoqiu, WANG Jing, LI Zhuowei, CHEN Yukun, CHEN Kezhong   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Synchronous and Metachronous Diagnosis of Multiple Primary Cancers

, 1998
Aims In the time period near to the diagnosis of a new cancer, other tumors (synchronous cancers), especially slow-growing tumors, may be detected because several diagnostic examinations are performed.
Stefania Arniani, Eva Buiatti, Emanuele Crocetti   +2 more
core   +1 more source

Multiple primary cancers associated with merkel cell carcinoma in Queensland, Australia, 1982-2011 [PDF]

, 2014
The relatively high incidence of Merkel cell carcinoma (MCC) in Queensland provides a valuable opportunity to examine links with other cancers. A retrospective cohort study was performed using data from the Queensland Cancer Registry.
Baade, Peter D., Baade, Peter D, Youlden, Danny, Baade, Peter, Soyer, H. Peter, Fritschi, L, Baade, P D, Youl, Philippa, Baade, P., Soyer, H Peter, Youl, Philippa H., Peter Soyer, H, Fritschi, Lin, Peter Soyer, H., Youlden, D R, Youlden, D., Youl, P., Youlden, Danny R., Youl, Philippa H, Youlden, Danny R, Soyer, H.   +20 more
core   +1 more source

Analysis of polymorphisms in genes associated with the FA/BRCA pathway in three patients with multiple primary malignant neoplasms

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Cases of more than three primary cancers are very rare. This study analyzed the genetic susceptibility of gene polymorphisms in three patients with multiple primary malignant neoplasms and examined the possible pathogenesis.
Le Wang, Hao Wang, Ting Wang, Jinhui Liu, Wei Chen, Yamin Wang, Chao Chen, Hongli Zhu, Penggao Dai   +8 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source