Results 141 to 150 of about 12,302,946 (299)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Prognostic value of hTERT mRNA expression in surgical samples of lung cancer patients : the European Early Lung Cancer Project

, 2010
Lung cancer is the most important cause of cancer-related mortality. Resectability and eligibility for treatment with adjuvant chemotherapy is determined by staging according to the TNM classification.
Heideman, Danielle A.M., Sozzi, Gabriella, Elborn, J. Stuart, Postmus, Pieter E., O'Byrne, Ken J., Martinet, Yves, Niklinski, Jacek, Sutedja, G. Thomas, Smit, Egbert F., Becker, Heinrich D., Van Den Berg, Remco M., Brambilla, Christian, Montuenga, Luis M., Meijer, Chris J.L.M., Snijders, Peter J.F., Brokx, Hes, Field, John K., Vesin, Aurelien, Risch, Angela, Thunnissen, Frederick B., Harrison, David J.   +20 more
core   +1 more source

Case report of multiple primary cancers and results of genetic testing to preliminarily explore their pathogenesis

SAGE Open Medical Case Reports
The occurrence of multiple primary malignancies in a single patient has been relatively rare. We report here the case of a 71-year-old man with three primary tumors of lung cancer, intrahepatic cholangiocarcinoma, and prostate cancer, and a preliminary ...
Zhao Hong, Zhang Tongsong, Chen Cunhai, Li Xiao, Song Haiping   +4 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Synchronous Multiple Primary Lung Cancer [PDF]

C68. THORACIC ONCOLOGY CASE REPORTS II, 2020
M. Shallcross, V. Pathak
openaire   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

COPD in primary lung cancer patients: prevalence and mortality

, 2016
Elinor Ytterstad,1 Per C Moe,2 Audhild Hjalmarsen3 1Department of Mathematics and Statistics, UiT The Arctic University of Norway, 2Department of Pulmonary Medicine, University Hospital of North Norway, 3Department of Clinical Medicine, UiT The Arctic ...
Hjalmarsen A, Ytterstad E, Moe PC
core  

Extra‐Adrenal Paraganglioma Mimicking a Hilar Lymph Node Metastasis From Testicular Cancer: A Case Study

Thoracic Cancer
Extra‐adrenal paraganglioma is a rare tumor and is difficult to diagnose. We report a case of extra‐adrenal paraganglioma in the hilum identified after treatment for multiple intrathoracic lymph node metastases from testicular cancer.
Marina Nakatsuka, Satoshi Takamori, Takanobu Kabasawa, Shuichi Shimada, Makoto Endo, Satoshi Shiono   +5 more
doaj   +1 more source

Diagnostic Challenges in Differentiating Multiple Primary Lung Cancer from Intrapulmonary Metastasis: A Clinical Case Report

Lietuvos Chirurgija
Background. Multiple primary lung cancers increasingly emerge in clinical practice due to improved imaging, prolonged patient survival, and growing recognition of this condition.
Rimantė Šalkauskaitė, Agnė Šimbelytė, Vytautas Jovaišas, Vytenis Bertašius, Žymantas Jagelavičius   +4 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source