Results 11 to 20 of about 346,833 (254)

Longitudinal relationships between disability and gait characteristics in people with MS

Scientific Reports, 2022
Longitudinal data are vital in order to understand intra individual gait changes with the progression of multiple sclerosis (MS). Therefore, the primary aim of this study was to explore the relationship between changes in disability with changes in major
Sapir Dreyer-Alster, Shay Menascu, Mark Dolev, Uri Givon, David Magalashvili, Anat Achiron, Alon Kalron   +6 more
doaj   +1 more source

Multiple sclerosis

Nature Reviews Disease Primers, 2018
Multiple sclerosis is a potentially progressive, autoimmune neurologic disorder of the central nervous system, resulting from an autoimmune attack on central nervous system white matter. It is a leading cause of neurologic symptoms in young adults, with no known cure.
Chris, Cotsapas, Mitja, Mitrovic, David, Hafler   +2 more
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Targeted cognitive game training enhances cognitive performance in multiple sclerosis patients treated with interferon beta 1-a

Journal of NeuroEngineering and Rehabilitation, 2021
Background Prevention of cognitive decline in Multiple Sclerosis (MS) is of major importance. We explored the effect of a 6 months computerized game training program on cognitive performance in MS patients with mild cognitive impairment. Methods This was
Shay Menascu, Roy Aloni, Mark Dolev, David Magalashvili, Keren Gutman, Sapir Dreyer-Alster, Franck Tarpin-Bernard, Ran Achiron, Gil Harari, Anat Achiron   +9 more
doaj   +1 more source

The MULTI-ACT model: the path forward for participatory and anticipatory governance in health research and care

Health Research Policy and Systems, 2022
The COVID-19 pandemic has unmasked even more clearly the need for research and care to form a unique and interdependent ecosystem, a concept which has emerged in recent years.
Paola Zaratin, Deborah Bertorello, Roberta Guglielmino, Danilo Devigili, Giampaolo Brichetto, Valentina Tageo, Gabriele Dati, Stephanie Kramer, Mario Alberto Battaglia, Monica Di Luca   +9 more
doaj   +1 more source

Multiple Sclerosis [PDF]

Journal of Clinical Investigation, 2012
Multiple sclerosis (MS) is a chronic, complex neurological disease with a variable clinical course in which several pathophysiological mechanisms such as axonal/ neuronal damage, demyelination, inflammation, gliosis, remyelination and repair, oxidative injury and excitotoxicity, alteration of the immune system as well as biochemical disturbances and ...
Alyssa, Nylander, David A, Hafler
openaire   +4 more sources

Cognitive rehabilitation in multiple sclerosis: Three digital ingredients to address current and future priorities

Frontiers in Human Neuroscience, 2023
Multiple sclerosis (MS) is a neurological chronic disease with autoimmune demyelinating lesions and one of the most common disability causes in young adults.
Andrea Tacchino, Jessica Podda, Valeria Bergamaschi, Ludovico Pedullà, Giampaolo Brichetto, Giampaolo Brichetto   +5 more
doaj   +1 more source

COVID-19 Vaccine Response in People with Multiple Sclerosis Treated with Dimethyl Fumarate, Diroximel Fumarate, Natalizumab, Ocrelizumab, or Interferon Beta Therapy

Neurology and Therapy, 2023
Background Some multiple sclerosis (MS) disease-modifying therapies (DMTs) impair responses to vaccines, emphasizing the importance of understanding COVID-19 vaccine immune responses in people with MS (PwMS) receiving different DMTs.
Aliya Jaber, Meera Patel, Andrew Sylvester, Mary Yarussi, J. Tamar Kalina, Jason P. Mendoza, Robin L. Avila, Matthew A. Tremblay   +7 more
doaj   +1 more source

Multiple sclerosis [PDF]

Mental Health Clinician, 2019
Abstract Multiple sclerosis is a chronic, unpredictable, and disabling disease. Significant advances have been made in recent years supporting an earlier, more accurate, diagnosis and have led to more than 15 disease-modifying therapies approved by the Food and Drug Administration for relapsing forms of multiple sclerosis.
Shilpa Klocke, Nicole Hahn
openaire   +4 more sources

RAM-589.555 favors neuroprotective and anti-inflammatory profile of CNS-resident glial cells in acute relapse EAE affected mice

Journal of Neuroinflammation, 2020
Background Targeting RNA polymerase-1 (POL1) machinery is a new strategy for suppression of multiple sclerosis (MS) relapse activity. Oral administration of POL1 inhibitor RAM-589.555, which is characterized by high permeability and bioavailability in ...
Rina Zilkha-Falb, Tatyana Rachutin-Zalogin, Lakota Cleaver, Michael Gurevich, Anat Achiron   +4 more
doaj   +1 more source

“I need personal experiences or some sort of documentation”: a qualitative study on where people with multiple sclerosis seek information on dietary and herbal supplements

BMC Complementary Medicine and Therapies, 2021
Background The use of dietary and herbal supplements (DIHES) is widespread among people with multiple sclerosis (PwMS). PwMS are a highly informed patient group, and they use several types of sources to seek information on subjects related to their ...
Sofie Bergien, Clara M. Petersen, Marie Lynning, Maria Kristiansen, Lasse Skovgaard   +4 more
doaj   +1 more source