Results 11 to 20 of about 452,167 (205)
Nature Reviews Disease Primers, 2018 Multiple sclerosis is a potentially progressive, autoimmune neurologic disorder of the central nervous system, resulting from an autoimmune attack on central nervous system white matter. It is a leading cause of neurologic symptoms in young adults, with no known cure.
Chris, Cotsapas +2 more
+11 more sources
Journal of Clinical Investigation, 2012 Multiple sclerosis (MS) is a chronic, complex neurological disease with a variable clinical course in which several pathophysiological mechanisms such as axonal/ neuronal damage, demyelination, inflammation, gliosis, remyelination and repair, oxidative injury and excitotoxicity, alteration of the immune system as well as biochemical disturbances and ...
Alyssa, Nylander, David A, Hafler
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Mental Health Clinician, 2019 Abstract Multiple sclerosis is a chronic, unpredictable, and disabling disease. Significant advances have been made in recent years supporting an earlier, more accurate, diagnosis and have led to more than 15 disease-modifying therapies approved by the Food and Drug Administration for relapsing forms of multiple sclerosis.
Shilpa Klocke, Nicole Hahn
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Global Advances in Health and Medicine, 2013 The management of multiple sclerosis (MS) is changing at a rapid rate, with the emergence of a host of new therapeutic interventions in various stages of development. Despite the enthusiasm with which the pharmaceutical industry is hailing these interventions, there remains a need for people involved in the management of MS to be circumspect regarding ...
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Seminars in Neurology, 2007 Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that commonly leads to inflammatory and atrophic brain pathology, often causing cognitive impairment. MS-associated cognitive impairment was first described over a century ago.
Ralph H B, Benedict, Julie H, Bobholz
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Nature Communications, 2019 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
International Multiple Sclerosis Genetics Consortium
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Family Perspectives on Clinical Research for Pediatric Multiple Sclerosis: Enhancing Equity
Journal of Patient Experience, 2021 Pediatric new drug trials are federally mandated, but family perspectives in multiple sclerosis (MS) research are limited. Due to MS chronicity and long-term medical system involvement, we obtained family views on research priorities and optimized ...
Leslie A Mandel PhD, MA, MS +7 more
doaj +1 more source
Frontiers in Neurology, 2023 BackgroundAlemtuzumab (ALZ) is a humanized monoclonal antibody approved for the treatment of patients with highly active relapsing-remitting multiple sclerosis (RRMS) administered in two annual courses.
Sara Eichau +7 more
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European Journal of Medical Research, 2023 Introduction Balance disorders are common in people with Multiple Sclerosis (PwMS) and, together with other impairments and disabilities, often prevent PwMS from performing their daily living activities.
Jessica Podda +9 more
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Frontiers in Neurology, 2021 Background: Although cognition in multiple sclerosis (MS) is assessed by means of several neuropsychological tests, only a few tools exist to investigate patients' perspectives on cognitive functioning.Objective: To develop a new questionnaire aimed at ...
Alice Riccardi +12 more
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