Results 31 to 40 of about 459,966 (302)

Standard versus innovative robotic balance assessment for people with multiple sclerosis: a correlational study

European Journal of Medical Research, 2023
Introduction Balance disorders are common in people with Multiple Sclerosis (PwMS) and, together with other impairments and disabilities, often prevent PwMS from performing their daily living activities.
Jessica Podda, Giorgia Marchesi, Valentina Squeri, Alice De Luca, Alice Bellosta, Ludovico Pedullà, Giovanna Konrad, Mario Alberto Battaglia, Giampaolo Brichetto, Andrea Tacchino   +9 more
doaj   +1 more source

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

Nature Communications, 2019
Genome-wide association studies (GWAS) have so far uncovered more than 200 loci for multiple sclerosis (MS). Here, the authors integrate data from various sources for a cell type-specific pathway analysis of MS GWAS results that specifically highlights ...
International Multiple Sclerosis Genetics Consortium
doaj   +1 more source

Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis

Frontiers in Immunology, 2021
Pregnancy affects the disease course in multiple sclerosis (MS), particularly in the third trimester, where the relapse rate is reduced by as much as two thirds.
Helle Bach Søndergaard, Laura Airas, Jeppe Romme Christensen, Birgitte Romme Nielsen, Lars Börnsen, Annette Oturai, Finn Sellebjerg   +6 more
doaj   +1 more source

Patterns of care for Multiple Sclerosis in a setting of universal care access: A cross-sectional study [PDF]

, 2019
BACKGROUND Current guidelines recommend regular neurological MS care in persons diagnosed with MS, but little is known about implementation of this recommendation or potential access barriers.
Rodgers, S., Kaufmann, Marco; https://orcid.org/, Kuhle, J., Puhan, M.A., Puhan, Milo A, Kuhle, Jens, Puhan, M. A., Kamm, Christian P, Kesselring, Jürg, Rodgers, Stephanie, Pot, Caroline, von Wyl, Viktor, Czaplinski, Adam, Barin, L., Kamm, C.P., von Wyl, V., Barin, Laura, Salmen, A., Ajdacic-Gross, Vladeta, Pot, C., Salmen, Anke, Kaufmann, M., Chan, A., Czaplinski, A., Kamm, Christian P., Swiss Multiple Sclerosis Registry, Chan, Andrew, Gobbi, C., Ajdacic-Gross, V., Gobbi, Claudio, Kesselring, J.   +30 more
core   +1 more source

Interleukin-33 plasma levels in patients with relapsing-remitting multiple sclerosis

Biomolecular Concepts, 2017
Cytokines are implicated in the immunopathogenesis of multiple sclerosis (MS). Interleukin (IL)-33, one of the recently discovered members of the IL-1 superfamily, is a dual functional cytokine involved in various autoimmune disorders.
Alsahebfosoul Fereshteh, Rahimmanesh Ilnaz, Shajarian Mansour, Etemadifar Masoud, Sedaghat Nahid, Hejazi Zahra, Naderi Shamsi   +6 more
doaj   +1 more source

Designing a Self-Perception Cognitive Questionnaire for Italian Multiple Sclerosis Patients (Sclerosi Multipla Autovalutazione Cognitiva, SMAC). A Preliminary Exploratory Pilot Study

Frontiers in Neurology, 2021
Background: Although cognition in multiple sclerosis (MS) is assessed by means of several neuropsychological tests, only a few tools exist to investigate patients' perspectives on cognitive functioning.Objective: To develop a new questionnaire aimed at ...
Alice Riccardi, Francesca Ognibene, Sara Mondini, Massimo Nucci, Monica Margoni, Ilaria Meglioranzi, Elisa Carta, Sofia Zywicki, Silvia Miante, Paola Perini, Francesca Rinaldi, Marco Puthenparampil, Paolo Gallo   +12 more
doaj   +1 more source

Functional clinical outcomes in multiple sclerosis: Current status and future prospects [PDF]

, 2015
For decades, the Expanded Disability Status Scale (EDSS) has been the principal measure of disability in clinical trials in patients with multiple sclerosis (MS) and in clinical practice.
Deleu, Dirk T., Dahdaleh, Maurice P., Alroughani, Raed, Inshasi, Jihad Said, Yamout, Bassem I., Bohlega, Saeed A., Sahraian, Mohammed A., AlTahan, Abdulrahman M., Rieckmann, Peter, Al-Jumah, Mohammed A., Alsharoqi, Isa Ahmed, Deleu, Dirk, Aljumah, Mohammed, Daif, Abdulkader Kader M., Karabudak, Rana, Alroughani, Raed A., Sahraian, Mohammad Ali, Inshasi, Jihad S., Dahdaleh, Maurice, Alsharoqi, I. Ahmed, Amous, Amer, Daif, Abdulkader   +21 more
core   +1 more source

Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper). [PDF]

, 2021
Multiple sclerosis is a complex, autoimmune-mediated disease of the central nervous system characterized by inflammatory demyelination and axonal/neuronal damage.
Hartung, H.P., Bittner, S., Guger, M., Lünemann, J.D., Berghoff, M., Tumani, H., Deisenhammer, F., Heidenreich, F., Meyding-Lamadé, U., Wiendl, H., Gehring, K., Gass, A., Schmidt, S., Enzinger, C., Weber, F., Haghikia, A., Berger, T., Linker, R., Mäurer, M., Leussink, V.I., Platten, M., Leutmezer, F., Zipp, F., Ziemssen, T., Lutterotti, A., Di Pauli, F., Fertl, E., Derfuss, T., Baum, K., Kallmann, B., Chan, A., Weber, M.S., Czaplinski, A., Aktas, O., Kleinschnitz, C., Hoffmann, O., Gobbi, C., Limmroth, V., Klotz, L., Gold, R., Rieckmann, P., Goebels, N., Zettl, U.K., Meuth, S.G., Du Pasquier, R.   +44 more
core   +1 more source

Blood RNA-Seq profiling reveals a set of circular RNAs differentially expressed in frail individuals

Immunity & Ageing, 2023
Background Frailty is an intermediate and reversible geriatric syndrome that often precedes dependence. Therefore, its identification is essential to prevent dependence. Several molecules have been proposed as biomarkers of frailty, but none of them have
Leire Iparraguirre, Ainhoa Alberro, Saioa GS Iñiguez, Maider Muñoz-Culla, Itziar Vergara, Ander Matheu, David Otaegui   +6 more
doaj   +1 more source

The Role of Microorganisms in the Etiopathogenesis of Demyelinating Diseases

Life, 2023
Multiple sclerosis (MS), neuromyelitis optica (NMO) and myelin oligodendrocyte glycoprotein antibody disease (MOGAD) are inflammatory diseases of the central nervous system (CNS) with a multifactorial aetiology.
Jessica Frau, Giancarlo Coghe, Lorena Lorefice, Giuseppe Fenu, Eleonora Cocco   +4 more
doaj   +1 more source