Results 11 to 20 of about 458,215 (302)

Multiple Sclerosis [PDF]

open access: yesNew England Journal of Medicine, 2018
Multiple sclerosis continues to be a challenging and disabling condition but there is now greater understanding of the underlying genetic and environmental factors that drive the condition, including low vitamin D levels, cigarette smoking, and obesity.
Peter A Calabresi, Daniel S Reich
exaly   +12 more sources

Longitudinal relationships between disability and gait characteristics in people with MS

open access: yesScientific Reports, 2022
Longitudinal data are vital in order to understand intra individual gait changes with the progression of multiple sclerosis (MS). Therefore, the primary aim of this study was to explore the relationship between changes in disability with changes in major
Sapir Dreyer-Alster   +6 more
doaj   +1 more source

Targeted cognitive game training enhances cognitive performance in multiple sclerosis patients treated with interferon beta 1-a

open access: yesJournal of NeuroEngineering and Rehabilitation, 2021
Background Prevention of cognitive decline in Multiple Sclerosis (MS) is of major importance. We explored the effect of a 6 months computerized game training program on cognitive performance in MS patients with mild cognitive impairment. Methods This was
Shay Menascu   +9 more
doaj   +1 more source

The MULTI-ACT model: the path forward for participatory and anticipatory governance in health research and care

open access: yesHealth Research Policy and Systems, 2022
The COVID-19 pandemic has unmasked even more clearly the need for research and care to form a unique and interdependent ecosystem, a concept which has emerged in recent years.
Paola Zaratin   +9 more
doaj   +1 more source

External validation of a clinical prediction model in multiple sclerosis [PDF]

open access: yes, 2023
Background: Timely initiation of disease modifying therapy is crucial for managing multiple sclerosis (MS). Objective: We aimed to validate a previously published predictive model of individual treatment response using a non-overlapping cohort from the ...
Inshasi, Jihad   +24 more
core   +1 more source

Challenges to Longitudinal Characterization of Lower Urinary Tract Dysfunction in Multiple Sclerosis [PDF]

open access: yes, 2022
Background: Neurogenic lower urinary tract dysfunction (LUTD) results in lower urinary tract symptoms (LUTS) that impact quality of life in people with multiple sclerosis (PwMS).
Saraceno, Taylor J.   +16 more
core   +1 more source

Treatment of multiple sclerosis in special populations: The case of refugees [PDF]

open access: yes, 2020
Multiple sclerosis was long considered a relatively rare entity in the Middle East, but research over the past 10 years and the publication of the Middle East North Africa Committee for Treatment and Research in Multiple Sclerosis guidelines for multiple
Yamout, Bassem I., Zeineddine, Maya M.
core   +1 more source

Multiple Sclerosis [PDF]

open access: yesSeminars in Neurology, 2007
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that commonly leads to inflammatory and atrophic brain pathology, often causing cognitive impairment. MS-associated cognitive impairment was first described over a century ago.
Ralph H B, Benedict, Julie H, Bobholz
  +5 more sources

Toxocara infection in the differential diagnosis of multiple sclerosis in the Middle East [PDF]

open access: yes, 2020
A critical step in the diagnosis of multiple sclerosis is to rule out a heterogeneous variety of multiple sclerosis mimickers, which is crucial in the era of powerful immune-modulator treatments.
El Najjar, Mayssam   +3 more
core   +1 more source

Multiple Sclerosis [PDF]

open access: yesJournal of Clinical Investigation, 2012
Multiple sclerosis (MS) is a chronic, complex neurological disease with a variable clinical course in which several pathophysiological mechanisms such as axonal/ neuronal damage, demyelination, inflammation, gliosis, remyelination and repair, oxidative injury and excitotoxicity, alteration of the immune system as well as biochemical disturbances and ...
Alyssa, Nylander, David A, Hafler
openaire   +4 more sources

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