Results 31 to 40 of about 755,873 (344)

Neuroprotection in a Novel Mouse Model of Multiple Sclerosis [PDF]

open access: yes, 2013
The authors acknowledge the support of the Barts and the London Charity, the Multiple Sclerosis Society of Great Britain and Northern Ireland, the National Multiple Sclerosis Society, USA, notably the National Centre for the Replacement, Refinement ...
A Compston   +49 more
core   +4 more sources

Standard versus innovative robotic balance assessment for people with multiple sclerosis: a correlational study

open access: yesEuropean Journal of Medical Research, 2023
Introduction Balance disorders are common in people with Multiple Sclerosis (PwMS) and, together with other impairments and disabilities, often prevent PwMS from performing their daily living activities.
Jessica Podda   +9 more
doaj   +1 more source

The clinical- and cost-effectiveness of functional electrical stimulation and ankle-foot orthoses for foot drop in Multiple Sclerosis: a multicentre randomized trial [PDF]

open access: yes, 2019
Objective: To compare the clinical- and cost-effectiveness of ankle-foot orthoses (AFOs) and functional electrical stimulation (FES) over 12 months in people with Multiple Sclerosis with foot drop.
Bowers, Roy   +7 more
core   +2 more sources

Coincident onset of multiple sclerosis and herpes simplex virus 1 encephalitis. a case report [PDF]

open access: yes, 2017
Background: Along with vitamin D, smoking, body mass index and others, Epstein Barr virus, other herpesviruses and human endogenous retroviruses represent plausible environmental risk factors for multiple sclerosis.
Buscarinu, M. C.   +7 more
core   +2 more sources

Multiple sclerosis.

open access: yesClinical evidence, 2002
▪ Abstract  Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system (CNS). Diagnosis rests upon identifying typical clinical symptoms and interpreting supportive laboratory and radiological investigations. The etiology is unknown; however, strong evidence suggests that MS is an autoimmune disease directed against CNS ...
Mike, Boggild, Helen, Ford
  +9 more sources

Interleukin-33 plasma levels in patients with relapsing-remitting multiple sclerosis

open access: yesBiomolecular Concepts, 2017
Cytokines are implicated in the immunopathogenesis of multiple sclerosis (MS). Interleukin (IL)-33, one of the recently discovered members of the IL-1 superfamily, is a dual functional cytokine involved in various autoimmune disorders.
Alsahebfosoul Fereshteh   +6 more
doaj   +1 more source

Reduction in circulating vitamin D binding protein in patients with multiple sclerosis

open access: yesBMC Neurology, 2021
Background In this study, we aimed to determine the risk association between vitamin D binding protein (VDBP) polymorphism in patients with multiple sclerosis (MS) in a MS biobank and the difference in VDBP serum levels in MS patients who were recently ...
Zhila Maghbooli   +4 more
doaj   +1 more source

Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models

open access: yesNeuroImage: Clinical, 2015
Magnetic resonance imaging (MRI) of the brain provides important outcome measures in the longitudinal evaluation of disease activity and progression in MS subjects. Two common measures derived from brain MRI scans are the brain parenchymal fraction (BPF)
Alicia S. Chua, MS   +8 more
doaj   +1 more source

Multiple Sclerosis [PDF]

open access: yesJournal of Clinical Investigation, 2012
Multiple sclerosis (MS) is a chronic, complex neurological disease with a variable clinical course in which several pathophysiological mechanisms such as axonal/ neuronal damage, demyelination, inflammation, gliosis, remyelination and repair, oxidative injury and excitotoxicity, alteration of the immune system as well as biochemical disturbances and ...
Alyssa, Nylander, David A, Hafler
openaire   +4 more sources

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

open access: yesNature Communications, 2019
Genome-wide association studies (GWAS) have so far uncovered more than 200 loci for multiple sclerosis (MS). Here, the authors integrate data from various sources for a cell type-specific pathway analysis of MS GWAS results that specifically highlights ...
International Multiple Sclerosis Genetics Consortium
doaj   +1 more source

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