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Background: Although cognition in multiple sclerosis (MS) is assessed by means of several neuropsychological tests, only a few tools exist to investigate patients' perspectives on cognitive functioning.Objective: To develop a new questionnaire aimed at ...
Alice Riccardi+12 more
doaj +1 more source
Interferon beta in multiple sclerosis: experience in a British specialist multiple sclerosis centre [PDF]
Background: The efficacy of interferon beta (IFN beta) is well established in relapsing-remitting multiple sclerosis (MS). However, the use of this drug in clinical practice is complex, especially because it is only partially effective, its long term ...
Dubois, B.D.+7 more
core +2 more sources
Interleukin-33 plasma levels in patients with relapsing-remitting multiple sclerosis
Cytokines are implicated in the immunopathogenesis of multiple sclerosis (MS). Interleukin (IL)-33, one of the recently discovered members of the IL-1 superfamily, is a dual functional cytokine involved in various autoimmune disorders.
Alsahebfosoul Fereshteh+6 more
doaj +1 more source
Using normalisation process theory to understand barriers and facilitators to implementing mindfulness-based stress reduction for people with multiple sclerosis [PDF]
Objectives: To study barriers and facilitators to implementation of mindfulness-based stress reduction for people with multiple sclerosis. Methods: Qualitative interviews were used to explore barriers and facilitators to implementation of ...
Mair, Frances S.+4 more
core +1 more source
▪ Abstract Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system (CNS). Diagnosis rests upon identifying typical clinical symptoms and interpreting supportive laboratory and radiological investigations. The etiology is unknown; however, strong evidence suggests that MS is an autoimmune disease directed against CNS ...
Mike, Boggild, Helen, Ford
+9 more sources
Multiple sclerosis (MS) is a chronic, complex neurological disease with a variable clinical course in which several pathophysiological mechanisms such as axonal/ neuronal damage, demyelination, inflammation, gliosis, remyelination and repair, oxidative injury and excitotoxicity, alteration of the immune system as well as biochemical disturbances and ...
Alyssa, Nylander, David A, Hafler
openaire +4 more sources
Magnetic resonance imaging (MRI) of the brain provides important outcome measures in the longitudinal evaluation of disease activity and progression in MS subjects. Two common measures derived from brain MRI scans are the brain parenchymal fraction (BPF)
Alicia S. Chua, MS+8 more
doaj +1 more source
Reduction in circulating vitamin D binding protein in patients with multiple sclerosis
Background In this study, we aimed to determine the risk association between vitamin D binding protein (VDBP) polymorphism in patients with multiple sclerosis (MS) in a MS biobank and the difference in VDBP serum levels in MS patients who were recently ...
Zhila Maghbooli+4 more
doaj +1 more source
Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis
Pregnancy affects the disease course in multiple sclerosis (MS), particularly in the third trimester, where the relapse rate is reduced by as much as two thirds.
Helle Bach Søndergaard+6 more
doaj +1 more source
Large-scale gene-expression studies and the challenge of multiple sclerosis. [PDF]
In multiple sclerosis, a complex neurodegenerative disorder, a combination of genetic and environmental factors results in inflammation and myelin damage.
Baranzini, Sergio E, Hauser, Stephen L
core +3 more sources