Results 141 to 150 of about 724,116 (324)

Color and Graphic Display (CGD): Programs for Multiple Sequence Alignment Analysis in Spreadsheet Software [PDF]

, 2000
Christian Delamarche
openalex   +1 more source

An enzyme‐linked immunosorbent assay (ELISA)‐based activity assay for AMP‐activated protein kinase (AMPK)

FEBS Open Bio, EarlyView.
Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley   +1 more source

Architected Lattices with a Topological Transition

Advanced Engineering Materials, EarlyView., 2023
This article develops topological metamaterials showing multidirectional two‐step deformation under compression by embedding contact‐enabled topological mechanisms into lattice structures. Experiments on 3D‐printed 2D and 3D lattices and finite element simulations are conducted to demonstrate the working principle of the topological metamaterials.
Shivam Agarwal, Lihua Jin
wiley   +1 more source

Combining multiple structure and sequence alignments to improve sequence detection and alignment: Application to the SH2 domains of Janus kinases [PDF]

, 2001
Bissan Al‐Lazikani, Felix B. Sheinerman, Barry Honig   +2 more
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

MAGUS+eHMMs: improved multiple sequence alignment accuracy for fragmentary sequences. [PDF]

Bioinformatics, 2022
Shen C, Zaharias P, Warnow T.
europepmc   +1 more source

Automatic Discovery of Sub-molecular Sequence Domains in Multi-aligned Sequences: A Dynamic Programming Algorithm for Multiple Alignment Segmentation [PDF]

, 2001
Eric Poe Xing, Denise M. Wolf, Inna Dubchak, Sylvia J. Spengler, Manfred Zorn, Ilya Muchnik, Casimir A. Kulikowski   +6 more
openalex   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

MAGUS: Multiple sequence Alignment using Graph clUStering. [PDF]

Bioinformatics, 2021
Smirnov V, Warnow T.
europepmc   +1 more source

Sequence Flow: interactive web application for visualizing partial order alignments

BMC Genomics
Background Multiple sequence alignment (MSA) has proven extremely useful in computational biology, especially in inferring evolutionary relationships via phylogenetic analysis and providing insight into protein structure and function.
Krzysztof Zdąbłasz, Anna Lisiecka, Norbert Dojer   +2 more
doaj   +1 more source