Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Computational drug screening against the SARS-CoV-2 Saudi Arabia isolates through a multiple-sequence alignment approach. [PDF]
Mok PL +5 more
europepmc +1 more source
Exam‐level analysis of lecture capture viewing and student exam performance
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley +1 more source
Improving prediction accuracy in chimeric proteins with windowed multiple sequence alignment. [PDF]
Vedula S, Bronstein AM, Marx A.
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
ReAlign-P: a vertical iterative realignment method for protein multiple sequence alignment. [PDF]
Zhai Y, Zhang P, Zou Q, Luo X.
europepmc +1 more source
ClipKIT: A multiple sequence alignment trimming software for accurate phylogenomic inference. [PDF]
Steenwyk JL +4 more
europepmc +1 more source
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
A List-Based Parallel Bacterial Foraging Algorithm for the Multiple Sequence Alignment Problem. [PDF]
Rios-Willars E +2 more
europepmc +1 more source
Multiple Sequence Alignments: The Next Generation
Kazutaka Katoh, Kazuharu Misawa
openalex +2 more sources

